Phenylacetone

Phenylacetone
Phenylacetone
Identifiers
CAS number 103-79-7 YesY
ChemSpider 21106366 YesY
UNII O7IZH10V9Y YesY
KEGG C15512 YesY
ChEBI CHEBI:52052 YesY
Jmol-3D images Image 1
Properties
Molecular formula C9H10O
Molar mass 134.18 g mol−1
Density 1.006 g/mL
Melting point

-15 °C

Boiling point

214 — 216 °C

 YesY (verify) (what is: YesY/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Phenylacetone (known also as phenyl-2-propanone, benzyl methyl ketone, or methyl benzyl ketone), is an organic compound. It is a clear oil with a refractive index of 1.5168. This substance is used in the manufacture of methamphetamine and amphetamine as a starting material or intermediate, where it is commonly known as P2P. Due to the illicit uses in clandestine chemistry, it was declared a schedule II controlled substance in the United States 11. February 1980.[1]

Preparation

There are many methods in the scientific literature to prepare phenylacetone, and due to its status as a controlled substance, there is crossover into popular literature such as works by Uncle Fester and Alexander Shulgin. Large amounts of data are available on the Internet relating to the preparation of phenylacetone.

A conceptually simple example of phenylacetone organic synthesis is the Friedel-Crafts alkylation of benzene with chloroacetone.

Phenylacetone synthesis via the Friedel-Crafts acylation of benzene with chloroacetone.

Phenylacetone can also be produced from many other compounds. For example:


Phenyl acetone is used as an intermediate to produce pesticides and anticoagulants. Active ingredients as anticoagulant include:

See also

  • MDP2P - related compound with a methylenedioxy group, and a precursor to MDMA.

References


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