n-Propyl azide

n-Propyl azide
n-Propyl azide
Identifiers
CAS number 22293-25-0 YesY
Jmol-3D images Image 1
Properties
Molecular formula C3H7N3
Molar mass 85.11 g mol−1
Hazards
Main hazards Harmful, Explosive
Related compounds
Related compounds Hydrazoic acid, Chlorine azide, Ethyl azide
 YesY azide (verify) (what is: YesY/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

n-Propyl azide is a covalent molecule related to hydrazoic acid and other alkyl azides.[1]

n-Propyl azide has been used in the laboratory synthesis of pharmaceutical drug candidates.[2][3]

References

  1. ^ Stefan Bräse (Editor), Klaus Banert (Co-Editor); Organic Azides: Syntheses and Applications; 2010 John Wiley and Sons; ISBN 978-0-470-51998-1
  2. ^ Helmut Haning et al (2005). "Comparison of different heterocyclic scaffolds as substrate analog PDE5 inhibitors". Bioorganic & Medicinal Chemistry Letters 15 (17): 3900–3907. 
  3. ^ Michael H. Parker et al (2002). "Synthesis of (-)-5,8-Dihydroxy-3R-methyl-2R-(dipropylamino)-1,2,3,4-tetrahydronaphthalene: An Inhibitor of β-Amyloid1-42 Aggregation". Bioorganic & Medicinal Chemistry 10 (11): 3565–3569. 

Further reading

  • Edward J. Kaufmann, Richard C. Thompson (1977). "Reduction of organic azides by chromium(II) in aqueous solution". JACS 99 (6): 1824–1830. doi:10.1021/ja00448a025.