Gadoteric acid

Gadoteric acid
Gadoteric acid
Systematic (IUPAC) name
gadolinium(+3) cation; 2-[4,7,10-tris(carboxymethyl)-1,4,7,10-tetrazacyclododec-1-yl]acetate
Clinical data
AHFS/ International Drug Names
Pregnancy cat.  ?
Legal status  ?
CAS number 72573-82-1 YesY
ATC code V08CA02
PubChem CID 3085828
KEGG D08007 YesY
Chemical data
Formula C16H25GdN4O8 
Mol. mass 558.64 g/mol
 N(what is this?)  acid (verify)

Gadoteric acid (trade names Artirem, Dotarem) is a macrocycle-structured gadolinium-based MRI contrast agent. It consists of the organic acid DOTA as a chelating agent, and gadolinium (Gd3+), and is used in form of the meglumine salt.[1] The drug is approved and used in a number of countries worldwide.[2]


  1. ^ Herborn, C. U.; Honold, E.; Wolf, M.; Kemper, J.; Kinner, S.; Adam, G.; Barkhausen, J. (2007). "Clinical Safety and Diagnostic Value of the Gadolinium Chelate Gadoterate Meglumine (Gd-DOTA)". Investigative Radiology 42 (1): 58–62. doi:10.1097/01.rli.0000248893.01067.e5. PMID 17213750.  edit
  2. ^ Gadoteric Acid