Systematic (IUPAC) name
Clinical data
Pregnancy cat.  ?
Legal status Schedule III (US)
CAS number 76-20-0
ATC code None
PubChem CID 6433
ChemSpider 6193 YesY
UNII 217727W28W YesY
Chemical data
Formula C8H18O4S2 
Mol. mass 242.356 g/mol
SMILES eMolecules & PubChem
 YesY(what is this?)  (verify)

Trional (Methylsulfonal) is a sedative-hypnotic[1] and anesthetic drug with GABAergic actions[citation needed]. It has similar effects to sulfonal, except it is faster acting.[2]


Trional was prepared and introduced by Eugen Baumann and Alfred Kast in 1888.[3]

Appeared in Agatha Christie's "Murder On The Orient Express", "And Then There Were None" and other novels as a sleep inducing sedative.

See also

  • Sulfonal
  • Tetronal


  1. ^ (1907). Merck's 1907 Index. N. Y.: Merck & Co., p. 448.
  2. ^ Sajous, Charles E. (1896). Annual of the Universal Medical Sciences
    Philadelphia: F. A. Davis, v. 5, p. A-156.
  3. ^ Drinkwater, H. (1924). Fifty years of medical progress, 1873-1922.
    New York: The Macmillan Company, p. 40.