Combination of
Sulfacetamide Sulfonamide antibacterial
Sulfur Keratolytic
Clinical data
Licence data US FDA:link
Pregnancy cat.  ?
Legal status Prescription only
Routes Topical
ATC code  ?
 YesY(what is this?)  (verify)

The drug combination sulfacetamide/sulfur is a topical acne medication manufactured by Medicis under the trade name Plexion and also available under other trade names such as Clenia, Prascion, and Avar. It combines sodium sulfacetamide, a sulfonamide antibiotic, and sulfur, a keratolytic agent.[1] It is available in four formulations: as a cleansing cloth, cleanser, topical suspension, and as a facial mask. The sulfacetamide inhibits the growth of the bacterium Propionibacterium acnes that is associated with acne, while sulfur facilitates the removal of dead skin cells to prevent clogged pores.[2]


  1. ^ "PLEXION (R) (sodium sulfacetamide 10% and sulfur 5%)" (in English). Medicis Inc.. Retrieved 2008-12-02. 
  2. ^ "PLEXION Prescribing information" (in English). Medicis. Retrieved 2008-12-02.