Spermiogenesis is the final stage of spermatogenesis which sees the maturation of spermatids into mature, motile spermatozoa.


The process of spermiogenesis is traditionally divided into four stages: the Golgi phase, the cap phase, the acrosomal phase, and the maturation stage. [ [http://anatomy.iupui.edu/courses/histo_D502/D502f04/lecture.f04/Malef04/Male%20Reproduction-06.htm ANAT D502 – Basic Histology ] ]

Golgi phase

The spermatids, which up until now have been mostly radially symmetrical, begin to develop polarity.

* The head forms at one end, and the Golgi apparatus creates enzymes that will become the acrosome.
* At the other end, it develops a thickened mid-piece, where the mitochondria gather and form an axoneme.

Spermatid DNA also undergoes packaging, becoming highly condensed. The DNA is packaged firstly with specific nuclear basic proteins, which are subsequently replaced with protamines during spermatid elongation. The resultant tightly packed chromatin is transcriptionally inactive.

Cap phase

The Golgi apparatus surrounds the now condensed nucleus, becoming the acrosomal cap.

Acrosomal phase

One of the centrioles of the cell elongates to become the tail of the sperm. A temporary structure called the "manchette" assists in this elongation.

During this phase, the developing spermatozoa orient themselves so that their tails point towards the center of the lumen, away from the epithelium.

Maturation phase

The excess cytoplasm, known as "residual bodies", is phagocytosed by surrounding Sertoli cells in the testes.


The mature spermatozoa are released from the protective Sertoli cells into the lumen of the seminiferous tubule and a process called "spermiation" then takes place, which removes the remaining unnecessary cytoplasm and organelles.

The resulting spermatozoa are now mature but lack motility, rendering them sterile. The non-motile spermatozoa are transported to the epididymis in "testicular fluid" secreted by the Sertoli cells with the aid of peristaltic contraction.

Whilst in the epididymis they acquire motility. However, transport of the mature spermatozoa through the remainder of the male reproductive system is achieved via muscle contraction rather than the spermatozoon's recently acquired motility. A glycoprotein coat over the acrosome prevents the sperm from fertilizing the egg prior to traveling through the male and female reproductive tracts. Capacitation of the sperm by the enzymes FPP (fertilization promoting peptide, produced by the male) and heparin (in the female reproductive tract) remove this coat and allow sperm to bind to the egg.


External links

* [http://www.mcb.arizona.edu/wardlab/spermio.html Images and video of spermiogenesis] - University of Arizona
* [http://www.med.yale.edu/obgyn/reproimmuno/courses/class11/sld012.htm Overview at yale.edu]

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Look at other dictionaries:

  • spermiogenesis — spermiogenesis. См. спермиогенез. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • spermiogenesis — [spʉr΄mē ō jen′ə sis] n. [ModL < spermium (< Gr spermeion, sperm < sperma: see SPERM1) + GENESIS] 1. Zool. the changing of a spermatid into a spermatozoon 2. SPERMATOGENESIS …   English World dictionary

  • Spermiogenesis — spermatozoidų susidarymas statusas T sritis gyvūnų raida, augimas, ontogenezė, embriologija atitikmenys: lot. Spermiogenesis ryšiai: platesnis terminas – spermatogeninis ciklas sinonimas – spermiogenezė …   Veterinarinės anatomijos, histologijos ir embriologijos terminai

  • Spermiogenesis — spermatozoidų formavimasis statusas T sritis histologija atitikmenys: lot. Spermiogenesis ryšiai: platesnis terminas – vyro lytiniai organai siauresnis terminas – antrinis spermatocitas siauresnis terminas – pirminis spermatocitas siauresnis… …   Medicininės histologijos ir embriologijos vardynas

  • Spermiogenesis — spermiogenezė statusas T sritis embriologija atitikmenys: lot. Spermiogenesis ryšiai: platesnis terminas – spermatogeninis ciklas siauresnis terminas – akrosoma siauresnis terminas – akrosomos pūslelė siauresnis terminas – chromatoidinis kūnas… …   Medicininės histologijos ir embriologijos vardynas

  • spermiogenesis — noun Etymology: New Latin, from spermium spermatozoon + o + Latin genesis Date: 1916 spermatogenesis; specifically transformation of a spermatid into a spermatozoon …   New Collegiate Dictionary

  • spermiogenesis — n. [Gr. sperma, seed; genesis, beginning] The formation of spermatozoa from the spermatids produced during the meiotic divisions of spermatocytes; spermateleosis …   Dictionary of invertebrate zoology

  • spermiogenesis — spermiogenetic /sperr mee oh jeuh net ik/, adj. /sperr mee oh jen euh sis/, n. Cell Biol. the development of a spermatozoon from a spermatid. [1915 20; < NL spermi , comb. form of sperma SPERM1 + O + GENESIS] * * * …   Universalium

  • spermiogenesis — noun The first stage of spermatogenesis …   Wiktionary

  • spermiogenesis — That segment of spermatogenesis during which immature spermatids become spermatozoa. [sperm + G. genesis, origin] * * * sper·mio·gen·e·sis .spər mē ō jen ə səs n, pl e·ses .sēz 1) SPERMATOGENESIS 2) transformation …   Medical dictionary

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