- Cannabis consumption
Cannabis can be vaporized or smoked with implements such as bongs and pipes. Many people can create a makeshift bong or pipe out of an apple or soda can. They can also roll a cigarette-like joint or cigar-like blunt.
Local methods have differed by the preparation of the cannabis plant before use, the parts of the cannabis plant which are used, and the treatment of the smoke before inhalation. In early times, as in some parts of Africa today, a pile of cannabis was simply thrown onto a fire and the smoke inhaled.
A vaporizer heats herbal cannabis to 185–210 degrees Celsius (365–410 °F), which causes the active ingredients to evaporate into a gas without burning the plant material (the boiling point of THC is 157 °C (315 °F). A lower proportion of carbon monoxide and other toxic chemicals is released than by smoking, although this may vary depending on the design of the vaporizer and the temperature at which it is set. A MAPS-NORML study using a Volcano vaporizer reported 95% THC and no toxins delivered in the vapor. However, an older study using less sophisticated vaporizers found some toxins.
As an alternative to smoking, cannabis may be consumed orally. However, the cannabis or its extract must be sufficiently heated or dehydrated to cause decarboxylation of its most abundant cannabinoid, tetrahydrocannabinolic acid, into psychoactive THC.
Although hashish is sometimes eaten raw or mixed with water, THC and other cannabinoids are more efficiently absorbed into the bloodstream when combined with butter and other lipids or, less so, dissolved in ethanol. The time to onset of effects depends strongly on stomach content, but is usually about an hour, and may continue for a considerable length of time, whereas the effects of smoking herbal cannabis are almost immediate, lasting a shorter time.
Smoking cannabis results in a significant loss of THC and other cannabinoids in exhaled smoke, by decomposition in high-temperature burning and, with a joint or large-bowl utensil, in smoke that escapes and is not inhaled. In contrast, all of the active constituents enter the body when cannabis is ingested. It has been shown that the primary active component of cannabis, Δ9-THC, is converted to the more psychoactive 11-hydroxy-THC by the liver. Titration to the desired effect by ingestion is more difficult than through inhalation, due to the long onset time for the effects.
Cannabis can also be consumed as a cannabis tea. Although THC is lipophilic and only slightly water soluble (with a solubility of 2.8 mg per liter), enough THC can be dissolved to make a mildly psychoactive tea. However, water-based infusions are generally considered to be an inefficient use of the herb.
To kill potentially dangerous Aspergillus and other microorganisms, researchers "Levitz and Diamond (1991) suggested baking marijuana in home ovens at 150 °C (302 °F), for five minutes before smoking. Oven treatment killed conidia of A. fumigatus, A. flavus, and did not degrade the active component of marijuana, tetrahydrocannabinol (THC)." However neither this nor some other suggested sterilization methods degrade microbial antigens or decompose the microbial toxins. Note that many cannabinoids evaporate below 150 °C (302 °F).
- ^ "Erowid Cannabis Vault : Spiritual Use #2". www.erowid.org. http://www.erowid.org/plants/cannabis/cannabis_spirit2.shtml.
- ^ "Cannabis and Cannabis Extracts: Greater Than the Sum of Their Parts?". www.haworthpress.com. http://www.omma1998.org/McPartland-Russo-JCANT%201(3-4)-2001.pdf. Retrieved 2011-01-25.
- ^ 1989. The Merck Index, 11th ed., Merck & Co., Rahway, New Jersey
- ^ Gieringer, Dale H.; Joseph St. Laurent, Scott Goodrich (2004). "Cannabis Vaporizer Combines Efficient Delivery of THC with Effective Suppression of Pyrolytic Compounds" (PDF). Journal of Cannabis Therapeutics 4 (1): 7–27. doi:10.1300/J175v04n01_02. http://www.maps.org/mmj/Gieringer-vaporizer.pdf. Retrieved 2006-04-21.
- ^ Gieringer, Dale. "Marijuana Water Pipe and Vaporizer Study". http://www.maps.org/news-letters/v06n3/06359mj1.html. Retrieved 2006-04-21.
- ^ "Does marijuana have to be heated to become psychoactive?". Cannabisculture.com. 2003-01-02. http://www.cannabisculture.com/articles/2794.html. Retrieved 2011-02-23.
- ^ Paulo Borini; Romeu Cardoso Guimarães; Sabrina Bicalho Borini (May 2004). "Possible hepatotoxicity of chronic marijuana usage". Sao Paulo Medical Journal 122 (3): 120–3. doi:10.1590/S1516-31802004000300007. PMID 1957518. http://www.scielo.br/scielo.php?pid=S1516-31802004000300007&script=sci_arttext&tlng=en. Retrieved 2006-05-02.
- ^ Cannabis consumption in the ChemIDplus database
- ^ Leslie Iversen (2003-04-08). "Cannabis and the brain. Invited review Brain". Brain (Brain – Oxford Journals) 126 (6): 1252–1270. doi:10.1093/brain/awg143. http://brain.oxfordjournals.org/cgi/content/full/126/6/1252. Retrieved 2011-02-23.
- ^ "Microbiological contaminants of marijuana". www.hempfood.com. http://www.hempfood.com/IHA/iha01205.html. Retrieved 2008-06-22.
Cannabis General Preparations Usage Effects Notable strains Organizations Culture
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