Dicobalt edetate

Dicobalt edetate
Dicobalt edetate
CAS number 36499-65-7 YesY
PubChem 71942
ChemSpider 64951 YesY
Jmol-3D images Image 1
Image 2
Molecular formula C10H12Co2N2O8.6H2O
Molar mass 406.08 g/mol
514.18 g/mol (hexahydrate)
 N edetate (verify) (what is: YesY/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Dicobalt edetate is the coordination compound with the approximate formula Co2(EDTA)(H2O)6.

Solutions of this solid have been used in Europe as an antidote to cyanide poisoning.[1]

It is a derivative of the (non-natural) amino acid ethylenediaminetetraacetate.


The compound is polymeric in the crystalline form. Half of the Co2+ ions are bound to the EDTA2− and the other Co2+ ions are bound to four water ligands as well as carboxylate ligands on the [Co(EDTA)]2− entity.[2] In aqueous solution, depolymerization occurs to give [Co(EDTA)]2− and [Co(H2O)6]2+ ions, each of which is kinetically labile and has a high affinity for cyanide. Oxidants would convert the [Co(EDTA)]2− into [Co(EDTA)], which would be unreactive toward cyanide because this complex would be "inert."[3]


  1. ^ Pickering WG (December 1985). "Cyanide toxicity and the hazards of dicobalt edetate". Br Med J (Clin Res Ed) 291 (6509): 1644. doi:10.1136/bmj.291.6509.1644-a. PMC 1418389. PMID 2866807. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1418389. 
  2. ^ E. F. K. Mccandlish, T. K. Michael; Rose, N. J.; Neal, J. A.; Lingafelter, E. C.; Rose, N. J. (1978). "Comparison of the Structures and Aqueous Solutions of [(O-Phenylenediaminetetraacetato(2-)]Cobalt(II) and [Ethylenediaminetetraacetato(2-)]Cobalt(II)". Inorg. Chem. 17 (6): 1383–94. doi:10.1021/ic50184a001. 
  3. ^ Dwyer, F. P.; Garvan, F. L.; Kirschner, Stanley (1960). "Resolution of the Ethylenediaminetetracetatocobaltate(III) Ion". Inorg. Synth.. Inorganic Syntheses 4: 192–4. doi:10.1002/9780470132371.ch61. ISBN 9780470132371.