Colforsin

Colforsin: Colforsin

Systematic (IUPAC) name

[(3R,4aR,5S,6S,6aS,10S,10aR,10bS)-5-acetyloxy-3-ethenyl-10,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-5,6,6a,8,9,10-hexahydro-2H-benzo[f]chromen-6-yl] 3-dimethylaminopropanoate

Clinical data

AHFS/Drugs.com International Drug Names

Pregnancy cat. ?

Legal status ℞ Prescription only

Identifiers

CAS number 138605-00-2^Y

ATC code None

PubChem CID 444028

UNII 1F7A44V6OU^Y

KEGG D01697^Y

Chemical data

Formula C₂₇H₄₃N O₈

Mol. mass 509.631 g/mol

SMILES eMolecules & PubChem

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Colforsin (INN) is a water-soluble derivative of forskolin.

References

Mori M, Takeuchi M, Takaoka H, Hata K, Hayashi Y, Yokoyama M (August 1994). "Effect of NKH477, a new water-soluble forskolin derivative, on arterial-ventricular coupling and mechanical energy transduction in patients with left ventricular systolic dysfunction: comparison with dobutamine". J. Cardiovasc. Pharmacol. 24 (2): 310–6. doi:10.1097/00005344-199424020-00018. PMID 7526066.

Sanbe A, Takeo S (July 1995). "Effects of NKH477, a water-soluble forskolin derivative, on cardiac function in rats with chronic heart failure after myocardial infarction". J. Pharmacol. Exp. Ther. 274 (1): 120–6. PMID 7616388. http://jpet.aspetjournals.org/cgi/pmidlookup?view=long&pmid=7616388.

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Academic Dictionaries and Encyclopedias


Systematic (IUPAC) name
[(3R,4aR,5S,6S,6aS,10S,10aR,10bS)-5-acetyloxy-3-ethenyl-10,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-5,6,6a,8,9,10-hexahydro-2H-benzo[f]chromen-6-yl] 3-dimethylaminopropanoate
Clinical data
AHFS/Drugs.com	International Drug Names
Pregnancy cat.	?
Legal status	℞ Prescription only
Identifiers
CAS number	138605-00-2^Y
ATC code	None
PubChem	CID 444028
UNII	1F7A44V6OU^Y
KEGG	D01697^Y
Chemical data
Formula	C₂₇H₄₃N O₈
Mol. mass	509.631 g/mol
SMILES	eMolecules & PubChem
Y(what is this?) (verify)