Thymus hyperplasia

Thymus hyperplasia

Infobox_Disease
Name = PAGENAME


Caption =
DiseasesDB =
ICD10 = ICD10|E|32|0|e|20
ICD9 = ICD9|254.0
ICDO =
OMIM =
MedlinePlus =
eMedicineSubj =
eMedicineTopic =
MeshID = D013952

Thymus hyperplasia (or thymic hyperplasia) refers to an enlargent ("hyperplasia") of the thymus.cite web |url=http://www.emedicine.com/med/TOPIC3195.HTM#section~ThymicHyperplasia |title=eMedicine - Surgery of the Thymus Gland : Article by Said Fadi Yassin |format= |work= |accessdate=]

It is not always a disease state. The size of the thymus usually peaks during adolescence, and atrophies in the following decades. Before the immune function of the thymus was well understood, the enlargement was sometimes seen as a cause for alarm, and justification for surgical reduction. This approach is much less common today.

It can be associated with myasthenia gravis. [Medcyclopaedia|vii/t/thymus_hyperplasia] cite journal |author=Murakami M, Hosoi Y, Negishi T, "et al" |title=Thymic hyperplasia in patients with Graves' disease. Identification of thyrotropin receptors in human thymus |journal=J. Clin. Invest. |volume=98 |issue=10 |pages=2228–34 |year=1996 |month=November |pmid=8941638 |pmc=507671 |doi=10.1172/JCI119032 |url=http://dx.doi.org/10.1172/JCI119032]

MRI can be used to distinguish it from thymoma.cite journal |author=Inaoka T, Takahashi K, Mineta M, "et al" |title=Thymic hyperplasia and thymus gland tumors: differentiation with chemical shift MR imaging |journal=Radiology |volume=243 |issue=3 |pages=869–76 |year=2007 |month=June |pmid=17463136 |doi=10.1148/radiol.2433060797 |url=http://radiology.rsnajnls.org/cgi/pmidlookup?view=long&pmid=17463136]

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