Chronic mucocutaneous candidiasis

Chronic mucocutaneous candidiasis
Chronic mucocutaneous candidiasis
Classification and external resources
OMIM 607644 114580 212050
eMedicine derm/569
MeSH D002178

Chronic mucocutaneous candidiasis[1] is an immune disorder of T cells.[2] It is characterized by chronic infections with Candida that are limited to mucosal surfaces, skin, and nails.[3]:310 However, it can also be associated with other types of infections, such as human papilloma virus.[4]

An association with chromosome 2 has been identified.[5]

Types include:

Type OMIM Gene Locus
CANDF1 114580  ? 2p
CANDF2 212050 CARD9 9q34.3
CANDF3 607644  ? 11
CANDF4 613108 CLEC7A 12p13.2-p12.3
CANDF5 613953 IL17RA 22q11
CANDF6 613956 IL17F 6p12

See also


  1. ^ Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 1-4160-2999-0. 
  2. ^ "Chronic Mucocutaneous Candidiasis: Immunodeficiency Disorders: Merck Manual Home Edition". 
  3. ^ James, William D.; Berger, Timothy G. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0. 
  4. ^ "Chronic mucocutaneous candidiasis. DermNet NZ". 
  5. ^ Atkinson TP, Schäffer AA, Grimbacher B et al. (October 2001). "An immune defect causing dominant chronic mucocutaneous candidiasis and thyroid disease maps to chromosome 2p in a single family". Am. J. Hum. Genet. 69 (4): 791–803. doi:10.1086/323611. PMC 1226065. PMID 11517424.