Hereditary motor and sensory neuropathy

Hereditary motor and sensory neuropathy


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eMedicineSubj = neuro
eMedicineTopic = 468
MeshID = D015417

Hereditary motor and sensory neuropathies (HMSN) are a group of neuropathies which are characterized by their impact upon both afferent and efferent neural communication.

They are more common than hereditary sensory and autonomic neuropathies.cite journal |author=Houlden H, Blake J, Reilly MM |title=Hereditary sensory neuropathies |journal=Curr. Opin. Neurol. |volume=17 |issue=5 |pages=569–77 |year=2004 |month=October |pmid=15367861 |doi= |url=]


In 1968, it was classified from groups I to VII:cite web |url= |title=eMedicine - Charcot-Marie-Tooth and Other Hereditary Motor and Sensory Neuropathies : Article by Aamir Hashmat |format= |work= |accessdate=] cite journal |author=Dyck PJ, Lambert EH |title=Lower motor and primary sensory neuron diseases with peroneal muscular atrophy. I. Neurologic, genetic, and electrophysiologic findings in hereditary polyneuropathies |journal=Arch. Neurol. |volume=18 |issue=6 |pages=603–18 |year=1968 |month=June |pmid=4297451 |doi= |url=]

HMSN is sometimes equated with Charcot-Marie-Tooth disease.cite journal |author=Horacek O, Mazanec R, Morris CE, Kobesova A |title=Spinal deformities in hereditary motor and sensory neuropathy: a retrospective qualitative, quantitative, genotypical, and familial analysis of 175 patients |journal=Spine |volume=32 |issue=22 |pages=2502–8 |year=2007 |month=October |pmid=18090092 |doi=10.1097/BRS.0b013e3181573d4e |url=] cite journal |author=Bertorini T, Narayanaswami P, Rashed H |title=Charcot-Marie-Tooth disease (hereditary motor sensory neuropathies) and hereditary sensory and autonomic neuropathies |journal=Neurologist |volume=10 |issue=6 |pages=327–37 |year=2004 |month=November |pmid=15518599 |doi=10.1097/01.nrl.0000145596.38640.27 |url=]


Further reading


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