Plasma glycoproteins of the a-2-globulin class that inhibit the proteolytic activity of thrombin and serve to regulate the process of blood clotting.

Dictionary of molecular biology. 2004.

Look at other dictionaries:

  • Antithrombin — Serpin peptidase inhibitor, clade C (antithrombin), member 1 Antithrombin monomer drawn from PDB 2ANT …   Wikipedia

  • antithrombin — Any substance that inhibits or prevents the effects of thrombin in such a manner that blood does not coagulate. A deficiency of a. results in impaired inhibition of coagulation factors IIa, IXa, and Xa in plasma, causing recurrent thrombosis. a.… …   Medical dictionary

  • Serpin — Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. The name serpin is derived from this activity serine protease inhibitors. [cite journal |author=R. Carrell and J.… …   Wikipedia

  • anticoagulant — Substance that inhibits the clotting of blood. The most commonly used are EDTA and citrate (both of which work by chelating calcium) and heparin (that interferes with thrombin, probably by potentiating antithrombins). Other compounds such as… …   Dictionary of molecular biology

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