Disease of joints due to mechanical trauma. There is major disturbance in homeostasis of extracellular matrix with cartilage degradation (involving matrix metalloproteinases) and loss of normal joint function. Unlike rheumatoid arthritis there is not an autoimmune element and, though there is inflammation, it is generally considered to be secondary rather than causative.
Dictionary of molecular biology. 2004.
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Osteoarthritis — Classification and external resources ICD 10 M15 M … Wikipedia
osteoarthritis — ► NOUN Medicine ▪ degeneration of joint cartilage, causing pain and stiffness … English terms dictionary
osteoarthritis — [äs΄tē ō är thrīt′is] n. [ OSTEO + ARTHRITIS] a slowly progressive form of arthritis, found chiefly in older people, characterized by cartilage deterioration and bone enlargement … English World dictionary
Osteoarthritis — Mediale Gonarthrose MR Darstellung eines arthrotischen Kniegelenkes. Deutlich zu sehen sind die … Deutsch Wikipedia
osteoarthritis — /os tee oh ahr thruy tis/, n. Pathol. the most common form of arthritis, usually occurring after middle age, marked by chronic breakdown of cartilage in the joints leading to pain, stiffness, and swelling. Also called degenerative joint disease.… … Universalium
osteoarthritis — Arthritis characterized by erosion of articular cartilage, either primary or secondary to trauma or other conditions, which becomes soft, frayed, and thinned with eburnation of subchondral bone and outgrowths of marginal osteophytes; pain and… … Medical dictionary
osteoarthritis — osteoarthrosis; n. a degenerative disease of joints resulting from wear of the articular cartilage, which may lead to secondary changes in the underlying bone. It can be primary or it can occur secondarily to abnormal load to the joint or damage… … The new mediacal dictionary
osteoarthritis — noun Etymology: New Latin Date: 1878 arthritis marked by degeneration of the cartilage and bone of joints • osteoarthritic adjective … New Collegiate Dictionary
osteoarthritis — noun A form of arthritis, affecting mainly older people, caused by chronic degeneration of the cartilage and synovial membrane of the joints, leading to pain and stiffness. Syn: degenerative arthritis … Wiktionary
Osteoarthritis — Gelenkentzündung … Universal-Lexikon