- clonal selection
The process whereby one or more clones, ie. cells expressing a particular gene sequence are selected by naturally-occurring processes from a mixed population. Generally the clonal selection is for general expansion by mitosis, particularly with reference to B-lymphocytes where selection with subsequent expansion of clones occurs as a result of antigenic stimulation only of those lymphocytes bearing the appropriate receptors.
Dictionary of molecular biology. 2004.
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Clonal selection — of lymphocytes: 1) A hematopoietic stem cell undergoes differentiation and genetic rearrangement to produce 2) immature lymphocytes with many different antigen receptors. Those that bind to 3) antigens from the body s own tissues are destroyed,… … Wikipedia
clonal selection — noun (biology) In a young mammal, the method of immunoglobulin production ensuring that there is a large lymphocyte population with a wide variety of antigen binding sites, so that when a foreign antigen binds to a lymphocyte it will stimulate… … Useful english dictionary
clonal selection — The production of a population of plasma cells all producing the same antibody in response to the interaction between a B lymphocyte producing that specific antibody and the antigen bound by that antibody. See: primary immune response, secondary… … Glossary of Biotechnology
clonal selection theory — clonal selection theory. См. клонально селекционная теория. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) … Молекулярная биология и генетика. Толковый словарь.
Clonal Selection Algorithm — In Artificial immune systems, Clonal selection algorithms are a class of algorithms inspired by the clonal selection theory of acquired immunity that explains how B and T lymphocytes improve their response to antigens over time called affinity… … Wikipedia
clonal selection theory — a modification of the natural selection theory (q.v.): there are in each adult several million clones of antibody producing cells, each programmed to make antibody of a single specificity and bearing cell surface receptors capable of reacting… … Medical dictionary
Clonal — may refer to in Immunology Clonal deletion, a process by which B cells and T cells are deactivated before act significantly upon specific antigens Clonal selection theory, a model for how the immune system responds to infection Clonal anergy, a… … Wikipedia
clonal deletion theory — a theory of immunologic tolerance to self antigens according to which â€œforbidden clonesâ€ of immunocytes, those reactive with self antigens, are eliminated on contact with antigen during fetal life. The terms â€œclonal abortion,â€ â€œclonal… … Medical dictionary
clonal — ● clonal, clonale, clonaux adjectif Qui concerne le clone. clonal, ale, aux [klɔnal, o] adj. ÉTYM. 1961; de clone. → Clone. ❖ ♦ Biol. Relatif à un clone, aux clones, au clonage. || Sélection clo … Encyclopédie Universelle
Selección clonal — Teoría de Selección Clonal Esta teoría postula que cada antígeno estimulará a aquel linfocito o grupo de linfocitos que poseen en su membrana receptores capaces de reconocer y unirse específicamente a él y que como consecuencia se producía su… … Wikipedia Español