- cell line
A cell line is a permanently established cell culture that will proliferate indefinitely given appropriate fresh medium and space. Lines differ from cell strains in that they have escaped the Hayflick limit and become immortalized. Some species, particularly rodents, give rise to lines relatively easily, whereas other species do not. No cell lines have been produced from avian tissues, and the establishment of cell lines from human tissue is difficult. Many cell biologists would consider that a cell line is by definition already abnormal and that it is on the way towards becoming the culture equivalent of a neoplastic cell.
Dictionary of molecular biology. 2004.
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cell line — n a cell culture selected for uniformity from a cell population derived from a usu. homogeneous tissue source (as an organ) <a newly established cell line derived from human endometrial carcinoma (Biol. Abstracts)> * * * a cell culture that … Medical dictionary
cell line — cell line. См. клеточная линия. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) … Молекулярная биология и генетика. Толковый словарь.
cell line — noun : a cell culture selected for uniformity from a cell population derived from a usually homogeneous tissue source (as an organ) a newly established cell line derived from human endometrial carcinoma Biological Abstracts * * * Cell Biol. a… … Useful english dictionary
cell line — noun Date: 1951 a cell culture selected for uniformity from a cell population derived from a usually homogeneous tissue source (as an organ) < a newly established cell line derived from a human endometrial carcinoma Biological Abstracts > … New Collegiate Dictionary
cell line — Cell Biol. a perpetuating strain of cells in laboratory culture. [1950 55] * * * … Universalium
cell line — 1. A cell lineage that can be maintained in vitro. Significant genetic changes can occur during lengthy periods in culture, so that the genotype of long term cell lines may not be the same as that of the starter cell. 2. A cell lineage that can… … Glossary of Biotechnology
cell line — /ˈsɛl laɪn/ (say sel luyn) noun Biology a cell culture grown in a laboratory from an original cell or cells, which will proliferate indefinitely given the maintenance of favourable conditions. Compare cell strain … Australian English dictionary
cell line — noun Biology a cell culture developed from a single cell, consisting of cells with a uniform genetic make up … English new terms dictionary
cell line — noun A biological tissue or group of individual cells that are genetically identical as a result of dividing mitotically from a single progenitor cell … Wiktionary
Glial cell line-derived neurotrophic factor — Glial cell derived neurotrophic factor, also known as GDNF, is a small protein that potently promotes the survival of many types of neurons cite web | title = Entrez Gene: GDNF glial cell derived neurotrophic factor| url = http://www.ncbi.nlm.nih … Wikipedia