Calcium and calmodulin binding troponin T-like protein (34 kD) isolated from chicken gizzard and bovine aortic smooth muscle. Interacts with F-actin and tropomyosin in a calcium sensitive manner and acts as a regulator of smooth muscle contraction (inhibits when not phosphorylated). Distinct from caldesmon and myosin light chain kinase, but has some antigenic cross-reactivity with cardiac Troponin-T.

Dictionary of molecular biology. 2004.

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  • Calponin — protein Name = calponin 1, basic, smooth muscle caption = width = HGNCid = 2155 Symbol = CNN1 AltSymbols = EntrezGene = 1264 OMIM = 600806 RefSeq = NM 001299 UniProt = P51911 PDB = ECnumber = Chromosome = 19 Arm = p Band = 13.2 13.1… …   Wikipedia

  • calponin — noun Any of a family of proteins that binds calcium …   Wiktionary

  • calponin — cal·po·nin (kal poґnin) a calcium dependent actin binding protein of smooth muscle, existing in three isoforms (acidic, neutral, and basic); it also binds calmodulin and tropomyosin. It is a regulator of smooth muscle contraction, which it… …   Medical dictionary

  • Кальпонин — (англ. Calponin)  входит в семейство актин связывающих белков, типичные в основном для гладкомышечных клеток, связывающие G и F актин. Кальпонины являются продуктом 3 генов и подразделяются на так называемые α кальпонин (h1 или основная …   Википедия

  • LRCH4 — Leucine rich repeats and calponin homology (CH) domain containing 4, also known as LRCH4, is a human gene.cite web | title = Entrez Gene: LRCH4 leucine rich repeats and calponin homology (CH) domain containing 4| url =… …   Wikipedia

  • Muscle contraction — See also: Twitch and Tremor Top down view of skeletal muscle Muscle fiber generates tension through the action of actin and myosin cross bridge cycling. While under tension, the muscle may lengthen, shorten, or …   Wikipedia

  • Fimbrin — is an actin cross linking protein. To understand actin cross linking in context, one must first understand the function of actin itself within the cell. The actin monomer, known as G actin, is a globular protein that polymerizes helically to form …   Wikipedia

  • Actin-binding protein — Actin binding proteins (also known as ABP) are proteins that bind to actin. This may mean ability to bind actin monomers, or polymers, or both.Many actin binding proteins, including α actinin, β spectrin, dystrophin, utrophin and fimbrin, do this …   Wikipedia

  • Caldesmon — 1, also known as CALD1, is a human gene.cite web | title = Entrez Gene: CALD1 caldesmon 1| url = Cmd=ShowDetailView TermToSearch=800| accessdate = ] Caldesmon is a calmodulin binding protein. Like… …   Wikipedia

  • ACTA1 — Actin, alpha 1, skeletal muscle, also known as ACTA1, is a human gene. PBB Summary section title = summary text = Actin alpha 1 which is expressed in skeletal muscle is one of six different actin isoforms which have been identified. Actins are… …   Wikipedia

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