tumor necrosis factor
noun Date: 1975 a protein that is produced chiefly by monocytes and macrophages in response especially to endotoxins and that mediates inflammation and induces the destruction of some tumor cells and the activation of white blood cells

New Collegiate Dictionary. 2001.

Look at other dictionaries:

  • Tumor necrosis factor — can refer to: * Tumor necrosis factors, a class of cytokines * Tumor necrosis factor alpha, the most frequently mentioned member of this class, and what is referred to when the phrase Tumor necrosis factor is used without qualification * Tumor… …   Wikipedia

  • tumor necrosis factor — n a protein that is produced chiefly by monocytes and macrophages in response esp. to endotoxins, that mediates inflammation, and that induces the destruction of some tumor cells and the activation of white blood cells abbr. TNF * * * (TNF)… …   Medical dictionary

  • tumor necrosis factor — n. a protein produced by macrophages in response to bacterial infection: a form made by genetic engineering is used in the treatment of cancer …   English World dictionary

  • Tumor necrosis factor — Facteur de nécrose tumorale Pour les articles homonymes, voir TNF. En médecine, le tumor necrosis factor alpha (TNF), ou facteur nécrosant des tumeurs (TNFα, cachexine ou cachectine) est une importante cytokine impliquée dans l inflammation… …   Wikipédia en Français

  • tumor necrosis factor — noun a proinflammatory cytokine that is produced by white blood cells (monocytes and macrophages); has an antineoplastic effect but causes inflammation (as in rheumatoid arthritis) • Syn: ↑tumour necrosis factor, ↑TNF • Hypernyms: ↑cytokine * * * …   Useful english dictionary

  • tumor necrosis factor — TNF. A protein made by white blood cells in response to an antigen (substance that causes the immune system to make a specific immune response) or infection. TNF can also be made in the laboratory. It may boost a person’s immune response, and… …   English dictionary of cancer terms

  • tumor necrosis factor — a protein, produced in humans and other animals, that is destructive to cells showing abnormally rapid growth: identical with cachectin. Abbr.: TNF * * * …   Universalium

  • tumor necrosis factor — noun Any of several polypeptide hormones, produced by macrophages, that can destroy some cancer cells …   Wiktionary

  • tumor necrosis factor — tu′mor necro sis fac tor n. pha biochem. a protein, produced in humans and other animals, that is destructive to cells showing abnormally rapid growth Abbr.: TNF • Etymology: 1985–90 …   From formal English to slang

  • Tumor necrosis factor-alpha — Tumor necrosis factor (TNF, cachexin or cachectin and formally known as tumor necrosis factor alpha ) is a cytokine involved in systemic inflammation and is a member of a group of cytokines that all stimulate the acute phase reaction. TNF causes… …   Wikipedia

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