polyketide
noun Etymology: International Scientific Vocabulary poly- + ket- + -ide Date: 1927 any of a large class of diverse compounds that are characterized by more than two carbonyl groups connected by single intervening carbon atoms, that are produced especially by certain bacteria and fungi, and that include various substances (as erythromycin and lovastatin) having antibiotic, anticancer, cholesterol-lowering, or immunosuppressive effects

New Collegiate Dictionary. 2001.

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  • Polyketide — Als Polyketide bezeichnet man eine große Gruppe von Naturstoffen, die bezüglich ihrer chemischen Strukturen und pharmakologischen Eigenschaften äußerst heterogen zusammengesetzt ist. Gemeinsam ist ihnen die Biosynthese über den sogenannten… …   Deutsch Wikipedia

  • Polyketide — Polyketides are secondary metabolites from bacteria, fungi, plants, and animals. Polyketides are biosynthesized by the polymerization of acetyl and propionyl subunits in a similar process to fatty acid synthesis (a Claisen condensation). cite… …   Wikipedia

  • Polykétide — Polycétide Les polycétides [1] sont des métabolites secondaires de bactéries, champignons, végétaux et animaux qui proviennent de la condensation itérative de sous unités acétyle ou malonyle par des enzymes spécialisées les polycétides synthases… …   Wikipédia en Français

  • polyketide — noun a) Any polymer whose monomers is a ketide. b) Any of many biochemical intermediates, having such a structure, that occur in biosynthesis and metabolism. Syn: acetogenin …   Wiktionary

  • polyketide — poly·ke·tide .päl ē kē .tīd n any of a large class of diverse compounds that are characterized by more than two carbonyl groups connected by single intervening carbon atoms, that are produced esp. by certain bacteria and fungi, and that include… …   Medical dictionary

  • Polyketide synthase — Polyketide synthases, also known as PKSs, are a family of enzymes or enzyme complexes that produce polyketides, a large class of secondary metabolites, in bacteria, fungi, plants, and animals. The biosyntheses of polyketides share striking… …   Wikipedia

  • griseofulvin — Polyketide antibiotic from Penicillium griseofulvum. Used therapeutically as an antifungal. Blocks microtubule assembly and thus mitosis …   Dictionary of molecular biology

  • DEBS (6-deoxyerythronolide B synthase) — 6 Deoxyerythronolide B Synthase or DEBS has been identified as a Type 1 polyketide synthase. DEBS is found in Saccharopolyspora erythraea and responsible for the synthesis of the macrolide ring which is the precursor of the antibiotic… …   Wikipedia

  • Biosynthesis of doxorubicin — Doxorubicin (DXR) is a 14 hydroxylated version of daunorubicin, the immediate precursor of DXR in its biosynthetic pathway. Daunorubicin is more abundantly found as a natural product because it is produced by a number of different wild type… …   Wikipedia

  • Mycolactone — IUPAC name [(6S,7S,9E,12R) 12 [(E,2S,6R,7R,9R) 7,9 dihydroxy 4,6 dimethyldec 4 en 2 yl] 7,9 dimethyl 2 oxo 1 oxacyclodode …   Wikipedia

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