major histocompatibility complex
noun Date: 1972 a group of genes in mammals that code for cell-surface polymorphic glycoprotein molecules which display antigenic peptide fragments for T cell recognition and aid in the ability of the immune system to determine self from nonself

New Collegiate Dictionary. 2001.

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  • major histocompatibility complex — n a group of genes in mammals that function esp. in determining the histocompatibility antigens found on cell surfaces and that in humans comprise the alleles occurring at four loci on the short arm of chromosome 6 abbr. MHC * * * (MHC) the genes …   Medical dictionary

  • major histocompatibility complex — major histocompatibility complex. См. главный комплекс гистосовместимости. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • Major histocompatibility complex — The major histocompatibility complex (MHC) is a large genomic region or gene family found in most vertebrates that encodes MHC molecules. MHC molecules play an important role in the immune system and autoimmunity. Proteins are continually… …   Wikipedia

  • Major Histocompatibility Complex — Oberflächenmodell der MHC Klasse I (Links) und MHC Klasse II Proteinkomplexe (Rechts) mit den Untereinheiten (Orange und Rosa) und dem präsentierten Antigen (Rot). Der Haupthistokompatibilitätskomplex (Abk. MHC von engl. Major Histocompatibility… …   Deutsch Wikipedia

  • major histocompatibility complex — The set of gene loci specifying major histocompatibility antigens, eg. HLA in man, H 2 in mice, RLA in rabbits, RT 1 in rats, DLA in dogs, SLA in pigs, etc …   Dictionary of molecular biology

  • major histocompatibility complex — Abbreviation: MHC The large cluster of genes that encode the major histocompatibility antigens in mammals …   Glossary of Biotechnology

  • Major histocompatibility complex — Major histo|com|patibility com|plex [me̲ids̶c̶h̶er hißtokempätebịliti kạ̊mplekß; engl. = Haupthistokompatibilitätskomplex] m; : Gengruppe, die das Immunsystem steuert; Abk.: MHC …   Das Wörterbuch medizinischer Fachausdrücke

  • major histocompatibility complex — Immunol. See MHC. * * * ▪ genetics       group of genes that code for proteins found on the surfaces of cells that help the immune system recognize foreign substances. MHC proteins are found in all higher vertebrates. In human beings the complex… …   Universalium

  • major histocompatibility complex — noun : a group of genes that function especially in determining the histocompatibility antigens found on cell surfaces and that in man comprise the alleles occurring at four loci on the short arm of chromosome 6 abbreviation MHC …   Useful english dictionary

  • major histocompatibility complex — (MHC) A large set of cell surface molecules in each individual, encoded by a family of genes, that serves as a unique biochemical marker of individual identity. It can trigger T cell responses that may lead to rejection of transplanted tissues… …   Dictionary of microbiology

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