Langerhans cell
noun Etymology: Paul Langerhans died 1888 German physician Date: 1890 a cell that is found in the epidermis and functions as an antigen-presenting cell which binds antigen entering through the skin

New Collegiate Dictionary. 2001.

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  • Langerhans cell — Not to be confused with the beta cells making up the islets of Langerhans. Langerhans cells are dendritic cells abundant in epidermis, containing large granules called Birbeck granules. They are normally present in lymph nodes, and can be found… …   Wikipedia

  • Langerhans cell — Cell found in the skin that internalizes antigen and moves in the lymph to lymph nodes where it differentiates into a dendritic cell …   Dictionary of microbiology

  • Langerhans cell — Lang·er·hans cell läŋ ər .hän(t)s n a dendritic cell of the interstitial spaces of the mammalian epidermis that functions as an antigen presenting cell which binds antigen entering through the skin and transports it to the lymph nodes P.… …   Medical dictionary

  • langerhans cell — ˈläŋə(r)ˌhän(t)s noun Usage: usually capitalized L Etymology: after Paul Langerhans died 1888 German physician : a cell having slender cytoplasmic projections that is found in the epidermis and functions as an antigen presenting cell which binds… …   Useful english dictionary

  • Langerhans cell histiocytosis — Classification and external resources Micrograph showing a Langerhans cell histiocytosis with the characteristic reniform Langerhans cells accompanied by abundant eosinophils. H E stain …   Wikipedia

  • Langerhans cell histiocytosis multifocal — Langerhans cell histiocytosis occurring as erosive accumulations of proliferating Langerhans cells, commonly within the medullary cavities of bones, but also affecting the skin, gingiva, lungs, and stomach. It most commonly affects children and… …   Medical dictionary

  • Langerhans cell histiocytosis unifocal — Langerhans cell histiocytosis occurring as a single osteolytic lesion, usually in a long or flat bone; it may be asymptomatic or may produce bone pain, tenderness, and swelling and, sometimes, pathologic fracture …   Medical dictionary

  • Langerhans cell histiocytosis — any of a group of disorders characterized by proliferation of Langerhans cells, affecting children more often than adults. Lesions may be unifocal or multifocal and may involve the bone marrow, endocrine system, or lungs (the last being more… …   Medical dictionary

  • Langerhans cell histiocytosis — LCH. A group of rare disorders in which too many Langerhans cells (a type of white blood cell) grow in certain tissues and organs including the bones, skin, and lungs, and damage them. LCH may also affect the pituitary gland (which makes hormones …   English dictionary of cancer terms

  • Langerhans cell histiocytosis — overgrowth of cells of the reticuloendothelial system. This includes disorders previously called histiocytosis X, including eosinophilic granuloma, Hand Schüller Christian disease, and Letterer Siwe disease. P. Langerhans (1847 88), German… …   Medical dictionary

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