insulin-like growth factor
noun Date: 1976 either of two polypeptides structurally similar to insulin that are secreted either during fetal development or during childhood and that mediate growth hormone activity

New Collegiate Dictionary. 2001.

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  • Insulin-like growth factor — The insulin like growth factors (IGFs) are polypeptides with high sequence similarity to insulin. IGFs are part of a complex system that cells use to communicate with their physiologic environment. This complex system (often referred to as the… …   Wikipedia

  • Insulin-like growth factor — Kalottenmodell des IGF 1 nach NMR Strukturdaten.[1] Die Insulin like growth factors (IGF) (deutsch Insulinähnliche Wachstumsfaktoren) sind Polypeptide, die eine hohe Sequenzhomologie zu Insulin zeigen. Sie sind Teil ei …   Deutsch Wikipedia

  • insulin-like growth factor — in·su·lin like growth factor .in(t) s(ə )lən .līk n either of two polypeptides structurally similar to insulin that are secreted either during fetal development or during childhood and that mediate growth hormone activity esp insulin like growth… …   Medical dictionary

  • insulin-like growth factor — ˌ ̷ ̷  ̷ ̷  ̷ ̷ ˌ ̷ ̷ noun : either of two polypeptides structurally similar to insulin that are secreted either during fetal development or during childhood and that mediate growth hormone activity ; especially : insulin like growth factor 1 …   Useful english dictionary

  • Insulin-like Growth Factor — In|su|lin like Growth Fac|tor [ ɪnsjʊlɪn laɪk grəʊθ fæktə(r)], der; s: svw. ↑ Somatomedin …   Universal-Lexikon

  • insulin-like growth factor — IGFs I and II are polypeptides with considerable sequence similarity to insulin. They are capable of eliciting the same biological responses, including mitogenesis in cell culture. On the cell surface, there are two types of IGF receptor, one of… …   Dictionary of molecular biology

  • Insulin-like growth factor 1 — (IGF 1) that was once called somatomedin C, is a polypeptide protein hormone similar in molecular structure to insulin. It plays an important role in childhood growth and continues to have anabolic effects in adults. Production and circulationIGF …   Wikipedia

  • Insulin-like growth factor 2 — (IGF 2) is one of three protein hormones that share structural similarity to insulin. Gene structureIn humans, the IGF2 gene is located on chromosome 11p15.5, a region which contains numerous imprinted genes. In mice this homologous region is… …   Wikipedia

  • insulin-like growth factor 1 — wən n the juvenile form of insulin like growth factor that is produced chiefly by the liver in response to growth hormone with production declining after puberty abbr. IGF 1 …   Medical dictionary

  • Insulin-like growth factor 1 receptor — The Insulin like Growth Factor 1 (IGF 1) Receptor is a transmembrane receptor that is activated by IGF 1 and by the related growth factor IGF 2. It belongs to the large class of tyrosine kinase receptors. This receptor mediates the effects of IGF …   Wikipedia

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