Istradefylline

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IUPACName=8- [("E")-2-(3,4-dimethoxyphenyl)vinyl] -1,3-diethyl-7-methylpurine-2,6-dione
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PubChem=5311037
SMILES=CCN1C2=C(C(=O)N(C1=O)CC)N(C(=N2)C=CC3=CC(=C(C=C3)OC)OC)C
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Formula=C₂₀H₂₄N₄O₄
MolarMass=384.429 g/mol
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Istradefylline is an antagonist at the A_2A receptor. It has recently cite journal | author = Peter A. LeWitt, MD, M. Guttman, James W. Tetrud, MD, Paul J. Tuite, MD, Akihisa Mori, PhD, Philip Chaikin, PharmD, MD, Neil M. Sussman, MD | title = Adenosine A2A receptor antagonist istradefylline (KW-6002) reduces off time in Parkinson's disease: A double-blind, randomized, multicenter clinical trial (6002-US-005) | journal = Annals of Neurology | volume = 63 | issue = 3 | pages = 295-302 | year = 2008 | pmid = 18306243 | doi = 10.1002/ana.21315 | issn = ] been found to be useful in the treatment of Parkinson's Disease.

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