- BRDT
Bromodomain, testis-specific, also known as BRDT, is a human
gene .cite web | title = Entrez Gene: BRDT bromodomain, testis-specific| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=676| accessdate = ]PBB_Summary
section_title =
summary_text = BRDT is similar to the RING3 protein family. It possesses 2 bromodomain motifs and a PEST sequence (a cluster of proline, glutamic acid, serine, and threonine residues), characteristic of proteins that undergo rapid intracellular degradation. The bromodomain is found in proteins that regulate transcription. Two transcript variants encoding the same protein have been found for this gene.cite web | title = Entrez Gene: BRDT bromodomain, testis-specific| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=676| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Zheng Y, Yuan W, Zhou Z, "et al." |title=Molecular cloning and expression of a novel alternative splice variant of BRDT gene. |journal=Int. J. Mol. Med. |volume=15 |issue= 2 |pages= 315-21 |year= 2005 |pmid= 15647849 |doi=
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Pivot-Pajot C, Caron C, Govin J, "et al." |title=Acetylation-dependent chromatin reorganization by BRDT, a testis-specific bromodomain-containing protein. |journal=Mol. Cell. Biol. |volume=23 |issue= 15 |pages= 5354-65 |year= 2003 |pmid= 12861021 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Hartley JL, Temple GF, Brasch MA |title=DNA cloning using in vitro site-specific recombination. |journal=Genome Res. |volume=10 |issue= 11 |pages= 1788-95 |year= 2001 |pmid= 11076863 |doi=
*cite journal | author=Scanlan MJ, Altorki NK, Gure AO, "et al." |title=Expression of cancer-testis antigens in lung cancer: definition of bromodomain testis-specific gene (BRDT) as a new CT gene, CT9. |journal=Cancer Lett. |volume=150 |issue= 2 |pages= 155-64 |year= 2000 |pmid= 10704737 |doi=
*cite journal | author=Dhalluin C, Carlson JE, Zeng L, "et al." |title=Structure and ligand of a histone acetyltransferase bromodomain. |journal=Nature |volume=399 |issue= 6735 |pages= 491-6 |year= 1999 |pmid= 10365964 |doi= 10.1038/20974
*cite journal | author=Jones MH, Numata M, Shimane M |title=Identification and characterization of BRDT: A testis-specific gene related to the bromodomain genes RING3 and Drosophila fsh. |journal=Genomics |volume=45 |issue= 3 |pages= 529-34 |year= 1998 |pmid= 9367677 |doi= 10.1006/geno.1997.5000PBB_Controls
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