ELAVL3

ELAVL3

ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C), also known as ELAVL3, is a human gene.cite web | title = Entrez Gene: ELAVL3 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1995| accessdate = ]

PBB_Summary
section_title =
summary_text = A member of the ELAVL protein family, ELAV-like 3 is a neural-specific RNA-binding protein which contains three RNP-type RNA recognition motifs. The observation that ELAVL3 is one of several Hu antigens (neuronal-specific RNA-binding proteins) recognized by the anti-Hu serum antibody present in sera from patients with paraneoplastic encephalomyelitis and sensory neuronopathy (PEM/PSN) suggests it has a role in neurogenesis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.cite web | title = Entrez Gene: ELAVL3 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1995| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Behrends U, Jandl T, Golbeck A, "et al." |title=Novel products of the HUD, HUC, NNP-1 and alpha-internexin genes identified by autologous antibody screening of a pediatric neuroblastoma library. |journal=Int. J. Cancer |volume=100 |issue= 6 |pages= 669–77 |year= 2002 |pmid= 12209604 |doi= 10.1002/ijc.10550
*cite journal | author=Park S, Myszka DG, Yu M, "et al." |title=HuD RNA recognition motifs play distinct roles in the formation of a stable complex with AU-rich RNA. |journal=Mol. Cell. Biol. |volume=20 |issue= 13 |pages= 4765–72 |year= 2000 |pmid= 10848602 |doi=
*cite journal | author=Sakai K, Kitagawa Y, Hirose G |title=Analysis of the RNA recognition motifs of human neuronal ELAV-like proteins in binding to a cytokine mRNA. |journal=Biochem. Biophys. Res. Commun. |volume=256 |issue= 2 |pages= 263–8 |year= 1999 |pmid= 10079173 |doi= 10.1006/bbrc.1999.0282
*cite journal | author=Van Tine BA, Knops JF, Butler A, "et al." |title=Localization of HuC (ELAVL3) to chromosome 19p13.2 by fluorescence in situ hybridization utilizing a novel tyramide labeling technique. |journal=Genomics |volume=53 |issue= 3 |pages= 296–9 |year= 1998 |pmid= 9799595 |doi= 10.1006/geno.1998.5468
*cite journal | author=Sakai K, Gofuku M, Kitagawa Y, "et al." |title=A hippocampal protein associated with paraneoplastic neurologic syndrome and small cell lung carcinoma. |journal=Biochem. Biophys. Res. Commun. |volume=199 |issue= 3 |pages= 1200–8 |year= 1994 |pmid= 7511893 |doi= 10.1006/bbrc.1994.1358

PBB_Controls
update_page = yes
require_manual_inspection = no
update_protein_box = yes
update_summary = yes
update_citations = yes


Wikimedia Foundation. 2010.

Игры ⚽ Нужен реферат?

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”