Negri bodies

Micrograph with numerous rabies virions (small dark-grey rod-like particles) and Negri bodies, larger pathognomonic cellular inclusions of rabies infection.

Description: This micrograph depicts the histopathologic changes associated with rabies encephalitis prepared using an H&E stain. Note the Negri bodies, which are cellular inclusions found most frequently in the pyramidal cells of Ammon's horn, and the Purkinje cells of the cerebellum. They are also found in the cells of the medulla and various other ganglia.

Negri bodies are eosinophilic, sharply outlined, pathognomonic inclusion bodies (2–10 µm in diameter) found in the cytoplasm of certain nerve cells containing the virus of rabies, especially in Ammon's horn of the hippocampus. Often also found in the cerebellar cortex of postmortem brain samples of rabies victims.

They are named for Adelchi Negri.^[1]

References

1. ^ synd/2491 at Who Named It?

External links

• Negri+bodies at eMedicine Dictionary
• Slide at pathmicro.med.sc.edu - see bottom
• See pathology video of Negri bodies

This article related to pathology is a stub. You can help Wikipedia by expanding it.v · Categories: Histopathology Microbiology Rabies Pathology stubs Wikimedia Foundation. 2010. Игры ⚽ Нужно решить контрольную? Sally Thomsett Jack Zelig Look at other dictionaries: Negri bodies — oval or round inclusion bodies, seen in the cytoplasm and sometimes the processes of certain nerve cells in rabies; these are pathognomonic for the disease. Negri bodies (arrows) in cerebellar Purkinje cells in rabies encephalitis …   Medical dictionary Negri bodies — Ne·gri bodies (naґgre) [Adelchi Negri, Italian physician, 1876–1912] see under body …   Medical dictionary Negri bodies — (na gre) Masses of viruses or unassembled viral subunits found within the brain neurons of rabies infected animals …   Dictionary of microbiology Negri — may refer to: Negri bodies, in microbiology or to a place: Negri, Bacău, a commune in Bacău County, Romania or to a number of people: Ada Negri, an Italian poet Adelaida Negri, an Argentinian Soprano Antonio Negri, a political philosopher Cesare… …   Wikipedia Negri body — Ne·gri body nā grē n an inclusion body found in the nerve cells in rabies Negri Adelchi (1876 1912) Italian physician and pathologist. Negri conducted research in histology, hematology, cytology, protozoology, and hygiene. During histological… …   Medical dictionary negri body — ˈnāgrē noun Usage: usually capitalized N Etymology: after Adelchi Negri died 1912 Italian physician : an inclusion body found in the nerve cells in rabies * * * /nay gree/ any of the microscopic bodies found in the nerve cells of animals affected …   Useful english dictionary Negri body — /nay gree/ any of the microscopic bodies found in the nerve cells of animals affected with rabies. [1900 05; after A. Negri (1876 1912), Italian physician] * * * …   Universalium Negri — Adelchi, Italian physician, 1876–1912. See N. bodies, under body, N. corpuscles, under corpuscle …   Medical dictionary Adelchi Negri — (2 August 1876 – 19 February 1912) was an Italian pathologist and microbiologist who was born in Perugia. He studied medicine and surgery at the University of Pavia, where he was a pupil of Camillo Golgi (1843–1926). After graduation in 1900, he… …   Wikipedia Inclusion bodies — are nuclear or cytoplasmic aggregates of stainable substances, usually proteins. They typically represent sites of viral multiplication in a bacterium or a eukaryotic cell and usually consist of viral capsid proteins.CompositionProtein inclusion… …   Wikipedia 18+ © Academic, 2000-2024 Contact us: Technical Support, Advertising Dictionaries export, created on PHP, Joomla, Drupal, WordPress, MODx. Mark and share Search through all dictionaries Translate… Search Internet Share the article and excerpts Direct link … Do a right-click on the link above and select “Copy Link”