Nervonic acid

Nervonic acid
Nervonic acid[1]
Identifiers
CAS number 506-37-6 YesY
PubChem 5281120
ChemSpider 4444565 YesY
KEGG C08323 YesY
ChEBI CHEBI:44247 N
ChEMBL CHEMBL1173379 YesY
Jmol-3D images Image 1
Properties
Molecular formula C24H46O2
Molar mass 366.62 g/mol
Melting point

42-43 °C

 N acid (verify) (what is: YesY/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Nervonic acid is a monounsaturated omega-9 fatty acid. Nervonic acid has been identified as important in the biosynthesis of nerve cell myelin.[2] It is found in the sphingolipids of white matter in human brain.

Nervonic acid is used in the treatment of disorders involving demyelination, such as adrenoleukodystrophy and multiple sclerosis where there is a decreased level of nervonic acid in sphingolipids.[3]

Notes

  1. ^ Nervonic acid at Sigma-Aldrich
  2. ^ US Patent 6664406, Nervonic acid derivatives, their preparation and use
  3. ^ WO/1996/005740, Nervonic Acid Compositions

Additional references

  • Appelqvist (1976) Lipids in Cruciferae. In: Vaughan JG, Macleod AJ (Eds), The biology and the Chemistry of Cruciferae. Academic Press, London, UK, pp. 221-277.
  • Sargent JR, Coupland K, Wilson R (1994). Nervonic Acid and Demyelinating Disease. Medical Hypothesese 42, pp. 237-242.