RGS6

Regulator of G-protein signalling 6, also known as RGS6, is a human gene.cite web | title = Entrez Gene: RGS6 regulator of G-protein signalling 6| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9628| accessdate = ]

PBB_Summary
section_title =
summary_text = Members of the RGS (regulator of G protein signaling) family have been shown to modulate the functioning of G proteins by activating the intrinsic GTPase activity of the alpha (guanine nucleotide-binding) subunits. [supplied by OMIM] cite web | title = Entrez Gene: RGS6 regulator of G-protein signalling 6| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9628| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Sherrington R, Rogaev EI, Liang Y, "et al." |title=Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease. |journal=Nature |volume=375 |issue= 6534 |pages= 754–60 |year= 1995 |pmid= 7596406 |doi= 10.1038/375754a0
*cite journal | author=Seki N, Hattori A, Hayashi A, "et al." |title=The human regulator of G-protein signaling protein 6 gene (RGS6) maps between markers WI-5202 and D14S277 on chromosome 14q24.3. |journal=J. Hum. Genet. |volume=44 |issue= 2 |pages= 138–40 |year= 1999 |pmid= 10083744 |doi=
*cite journal | author=Snow BE, Betts L, Mangion J, "et al." |title=Fidelity of G protein beta-subunit association by the G protein gamma-subunit-like domains of RGS6, RGS7, and RGS11. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=96 |issue= 11 |pages= 6489–94 |year= 1999 |pmid= 10339615 |doi=
*cite journal | author=Posner BA, Gilman AG, Harris BA |title=Regulators of G protein signaling 6 and 7. Purification of complexes with gbeta5 and assessment of their effects on g protein-mediated signaling pathways. |journal=J. Biol. Chem. |volume=274 |issue= 43 |pages= 31087–93 |year= 1999 |pmid= 10521509 |doi=
*cite journal | author=Liu Z, Chatterjee TK, Fisher RA |title=RGS6 interacts with SCG10 and promotes neuronal differentiation. Role of the G gamma subunit-like (GGL) domain of RGS6. |journal=J. Biol. Chem. |volume=277 |issue= 40 |pages= 37832–9 |year= 2002 |pmid= 12140291 |doi= 10.1074/jbc.M205908200
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Chatterjee TK, Fisher RA |title=Mild heat and proteotoxic stress promote unique subcellular trafficking and nucleolar accumulation of RGS6 and other RGS proteins. Role of the RGS domain in stress-induced trafficking of RGS proteins. |journal=J. Biol. Chem. |volume=278 |issue= 32 |pages= 30272–82 |year= 2003 |pmid= 12761220 |doi= 10.1074/jbc.M212688200
*cite journal | author=Chatterjee TK, Liu Z, Fisher RA |title=Human RGS6 gene structure, complex alternative splicing, and role of N terminus and G protein gamma-subunit-like (GGL) domain in subcellular localization of RGS6 splice variants. |journal=J. Biol. Chem. |volume=278 |issue= 32 |pages= 30261–71 |year= 2003 |pmid= 12761221 |doi= 10.1074/jbc.M212687200
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Liu Z, Fisher RA |title=RGS6 interacts with DMAP1 and DNMT1 and inhibits DMAP1 transcriptional repressor activity. |journal=J. Biol. Chem. |volume=279 |issue= 14 |pages= 14120–8 |year= 2004 |pmid= 14734556 |doi= 10.1074/jbc.M309547200

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