PAQR8

Progestin and adipoQ receptor family member VIII
Identifiers
Symbols	PAQR8; C6orf33; FLJ32521; FLJ46206; LMPB1; MPRB
External IDs	OMIM: 607780 MGI: 1921479 HomoloGene: 32702 GeneCards: PAQR8 Gene
Gene Ontology Molecular function • receptor activity • steroid binding Cellular component • plasma membrane • integral to membrane Biological process • multicellular organismal development • cell differentiation • oogenesis Sources: Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	85315	74229
Ensembl	ENSG00000170915	ENSMUSG00000025931
UniProt	Q8TEZ7	Q80ZE5
RefSeq (mRNA)	NM_133367	NM_028829.3
RefSeq (protein)	NP_588608	NP_083105.3
Location (UCSC)	Chr 6: 52.23 – 52.27 Mb	Chr 1: 20.88 – 20.93 Mb
PubMed search	[1]	[2]

Membrane progestin receptor beta is a protein that in humans is encoded by the PAQR8 gene.^[1][2][3]

References

1. ^ Suzuki T, Ganesh S, Agarwala KL, Morita R, Sugimoto Y, Inazawa J, Delgado-Escueta AV, Yamakawa K (Oct 2001). "A novel gene in the chromosomal region for juvenile myoclonic epilepsy on 6p12 encodes a brain-specific lysosomal membrane protein". Biochem Biophys Res Commun 288 (3): 626–36. doi:10.1006/bbrc.2001.5825. PMID 11676489. 
2. ^ Zhu Y, Rice CD, Pang Y, Pace M, Thomas P (Mar 2003). "Cloning, expression, and characterization of a membrane progestin receptor and evidence it is an intermediary in meiotic maturation of fish oocytes". Proc Natl Acad Sci U S A 100 (5): 2231–6. doi:10.1073/pnas.0336132100. PMC 151323. PMID 12574519. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=151323. 
3. ^ "Entrez Gene: PAQR8 progestin and adipoQ receptor family member VIII". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=85315. 

Further reading

• Wistow G, Bernstein SL, Ray S, et al. (2002). "Expressed sequence tag analysis of adult human iris for the NEIBank Project: steroid-response factors and similarities with retinal pigment epithelium.". Mol. Vis. 8: 185–95. PMID 12107412. 
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241. 
• Zhu Y, Bond J, Thomas P (2003). "Identification, classification, and partial characterization of genes in humans and other vertebrates homologous to a fish membrane progestin receptor.". Proc. Natl. Acad. Sci. U.S.A. 100 (5): 2237–42. doi:10.1073/pnas.0436133100. PMC 151324. PMID 12601167. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=151324. 
• Hammes SR (2003). "The further redefining of steroid-mediated signaling.". Proc. Natl. Acad. Sci. U.S.A. 100 (5): 2168–70. doi:10.1073/pnas.0530224100. PMC 151311. PMID 12606724. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=151311. 
• Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6.". Nature 425 (6960): 805–11. doi:10.1038/nature02055. PMID 14574404. 
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. 
• Brandenberger R, Wei H, Zhang S, et al. (2005). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.". Nat. Biotechnol. 22 (6): 707–16. doi:10.1038/nbt971. PMID 15146197. 
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=528928. 
• Tang YT, Hu T, Arterburn M, et al. (2005). "PAQR proteins: a novel membrane receptor family defined by an ancient 7-transmembrane pass motif.". J. Mol. Evol. 61 (3): 372–80. doi:10.1007/s00239-004-0375-2. PMID 16044242.