ER degradation enhancer, mannosidase alpha-like 1, also known as EDEM1, is a human gene.cite web | title = Entrez Gene: EDEM1 ER degradation enhancer, mannosidase alpha-like 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9695| accessdate = ]

section_title =
summary_text =


Further reading

citations =
*cite journal | author=Nagase T, Seki N, Ishikawa K, "et al." |title=Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain. |journal=DNA Res. |volume=3 |issue= 5 |pages= 321–9, 341–54 |year= 1997 |pmid= 9039502 |doi=
*cite journal | author=Hosokawa N, Wada I, Hasegawa K, "et al." |title=A novel ER alpha-mannosidase-like protein accelerates ER-associated degradation. |journal=EMBO Rep. |volume=2 |issue= 5 |pages= 415–22 |year= 2001 |pmid= 11375934 |doi= 10.1093/embo-reports/kve084
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Oda Y, Hosokawa N, Wada I, Nagata K |title=EDEM as an acceptor of terminally misfolded glycoproteins released from calnexin. |journal=Science |volume=299 |issue= 5611 |pages= 1394–7 |year= 2003 |pmid= 12610305 |doi= 10.1126/science.1079181
*cite journal | author=Molinari M, Calanca V, Galli C, "et al." |title=Role of EDEM in the release of misfolded glycoproteins from the calnexin cycle. |journal=Science |volume=299 |issue= 5611 |pages= 1397–400 |year= 2003 |pmid= 12610306 |doi= 10.1126/science.1079474
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Olivari S, Galli C, Alanen H, "et al." |title=A novel stress-induced EDEM variant regulating endoplasmic reticulum-associated glycoprotein degradation. |journal=J. Biol. Chem. |volume=280 |issue= 4 |pages= 2424–8 |year= 2005 |pmid= 15579471 |doi= 10.1074/jbc.C400534200
*cite journal | author=Oda Y, Okada T, Yoshida H, "et al." |title=Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation. |journal=J. Cell Biol. |volume=172 |issue= 3 |pages= 383–93 |year= 2006 |pmid= 16449189 |doi= 10.1083/jcb.200507057
*cite journal | author=Hosokawa N, Wada I, Natsuka Y, Nagata K |title=EDEM accelerates ERAD by preventing aberrant dimer formation of misfolded alpha1-antitrypsin. |journal=Genes Cells |volume=11 |issue= 5 |pages= 465–76 |year= 2006 |pmid= 16629899 |doi= 10.1111/j.1365-2443.2006.00957.x
*cite journal | author=Ewing RM, Chu P, Elisma F, "et al." |title=Large-scale mapping of human protein-protein interactions by mass spectrometry. |journal=Mol. Syst. Biol. |volume=3 |issue= |pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134
*cite journal | author=Zuber C, Cormier JH, Guhl B, "et al." |title=EDEM1 reveals a quality control vesicular transport pathway out of the endoplasmic reticulum not involving the COPII exit sites. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=104 |issue= 11 |pages= 4407–12 |year= 2007 |pmid= 17360537 |doi= 10.1073/pnas.0700154104

update_page = yes
require_manual_inspection = no
update_protein_box = yes
update_summary = yes
update_citations = yes

Wikimedia Foundation. 2010.

Look at other dictionaries:

  • Hsp70 — protein Structure of the ATPase fragment of a 70K heat shock cognate protein.[1] Identifiers Symbol …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”