SLCO1A2

Solute carrier organic anion transporter family, member 1A2, also known as SLCO1A2, is a human gene.cite web | title = Entrez Gene: SLCO1A2 solute carrier organic anion transporter family, member 1A2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6579| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes a sodium-independent transporter which mediates cellular uptake of organic ions in the liver. Its substrates include bile acids, bromosulphophthalein, and some steroidal compounds. The protein is a member of the SLC21A family of solute carriers. Alternate splicing of this gene results in three transcript variants encoding two different isoforms.cite web | title = Entrez Gene: SLCO1A2 solute carrier organic anion transporter family, member 1A2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6579| accessdate = ]

ee also

* Solute carrier family

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Meier PJ, Eckhardt U, Schroeder A, "et al." |title=Substrate specificity of sinusoidal bile acid and organic anion uptake systems in rat and human liver. |journal=Hepatology |volume=26 |issue= 6 |pages= 1667–77 |year= 1998 |pmid= 9398014 |doi= 10.1002/hep.510260641
*cite journal | author=Kullak-Ublick GA, Hagenbuch B, Stieger B, "et al." |title=Molecular and functional characterization of an organic anion transporting polypeptide cloned from human liver. |journal=Gastroenterology |volume=109 |issue= 4 |pages= 1274–82 |year= 1995 |pmid= 7557095 |doi=
*cite journal | author=Kullak-Ublick GA, Beuers U, Meier PJ, "et al." |title=Assignment of the human organic anion transporting polypeptide (OATP) gene to chromosome 12p12 by fluorescence in situ hybridization. |journal=J. Hepatol. |volume=25 |issue= 6 |pages= 985–7 |year= 1997 |pmid= 9007731 |doi=
*cite journal | author=Kullak-Ublick GA, Beuers U, Fahney C, "et al." |title=Identification and functional characterization of the promoter region of the human organic anion transporting polypeptide gene. |journal=Hepatology |volume=26 |issue= 4 |pages= 991–7 |year= 1997 |pmid= 9328325 |doi= 10.1002/hep.510260429
*cite journal | author=Kullak-Ublick GA, Fisch T, Oswald M, "et al." |title=Dehydroepiandrosterone sulfate (DHEAS): identification of a carrier protein in human liver and brain. |journal=FEBS Lett. |volume=424 |issue= 3 |pages= 173–6 |year= 1998 |pmid= 9539145 |doi=
*cite journal | author=König J, Cui Y, Nies AT, Keppler D |title=Localization and genomic organization of a new hepatocellular organic anion transporting polypeptide. |journal=J. Biol. Chem. |volume=275 |issue= 30 |pages= 23161–8 |year= 2000 |pmid= 10779507 |doi= 10.1074/jbc.M001448200
*cite journal | author=Tamai I, Nezu J, Uchino H, "et al." |title=Molecular identification and characterization of novel members of the human organic anion transporter (OATP) family. |journal=Biochem. Biophys. Res. Commun. |volume=273 |issue= 1 |pages= 251–60 |year= 2000 |pmid= 10873595 |doi= 10.1006/bbrc.2000.2922
*cite journal | author=Speek M |title=Antisense promoter of human L1 retrotransposon drives transcription of adjacent cellular genes. |journal=Mol. Cell. Biol. |volume=21 |issue= 6 |pages= 1973–85 |year= 2001 |pmid= 11238933 |doi= 10.1128/MCB.21.6.1973-1985.2001
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Lee W, Glaeser H, Smith LH, "et al." |title=Polymorphisms in human organic anion-transporting polypeptide 1A2 (OATP1A2): implications for altered drug disposition and central nervous system drug entry. |journal=J. Biol. Chem. |volume=280 |issue= 10 |pages= 9610–7 |year= 2005 |pmid= 15632119 |doi= 10.1074/jbc.M411092200
*cite journal | author=Su Y, Zhang X, Sinko PJ |title=Human organic anion-transporting polypeptide OATP-A (SLC21A3) acts in concert with P-glycoprotein and multidrug resistance protein 2 in the vectorial transport of Saquinavir in Hep G2 cells. |journal=Mol. Pharm. |volume=1 |issue= 1 |pages= 49–56 |year= 2005 |pmid= 15832500 |doi=
*cite journal | author=Kimura K, Wakamatsu A, Suzuki Y, "et al." |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406

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