NARS (gene)

NARS (gene)
Asparaginyl-tRNA synthetase
Identifiers
Symbols NARS; ASNRS; NARS1
External IDs OMIM108410 MGI1917473 HomoloGene68404 GeneCards: NARS Gene
EC number 6.1.1.22
RNA expression pattern
PBB GE NARS 200027 at tn.png
PBB GE NARS 200028 s at tn.png
PBB GE NARS 200030 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 4677 70223
Ensembl ENSG00000134440 ENSMUSG00000024587
UniProt O43776 Q3T9A7
RefSeq (mRNA) NM_004539 NM_027350
RefSeq (protein) NP_004530 NP_081626
Location (UCSC) Chr 18:
55.27 – 55.29 Mb
Chr 18:
64.66 – 64.68 Mb
PubMed search [1] [2]

Asparaginyl-tRNA synthetase, cytoplasmic is an enzyme that in humans is encoded by the NARS gene.[1][2][3]

Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Asparaginyl-tRNA synthetase is localized to the cytoplasm and belongs to the class II family of tRNA synthetases. The N-terminal domain represents the signature sequence for the eukaryotic asparaginyl-tRNA synthetases.[3]

References

  1. ^ Cirullo RE, Arredondo-Vega FX, Smith M, Wasmuth JJ (May 1983). "Isolation and characterization of interspecific heat-resistant hybrids between a temperature-sensitive chinese hamster cell asparaginyl-tRNA synthetase mutant and normal human leukocytes: assignment of human asnS gene to chromosome 18". Somatic Cell Genet 9 (2): 215–33. doi:10.1007/BF01543178. PMID 6836455. 
  2. ^ Beaulande M, Tarbouriech N, Hartlein M (Feb 1998). "Human cytosolic asparaginyl-tRNA synthetase: cDNA sequence, functional expression in Escherichia coli and characterization as human autoantigen". Nucleic Acids Res 26 (2): 521–4. doi:10.1093/nar/26.2.521. PMC 147268. PMID 9421509. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=147268. 
  3. ^ a b "Entrez Gene: NARS asparaginyl-tRNA synthetase". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4677. 

Further reading



Wikimedia Foundation. 2010.

Игры ⚽ Нужен реферат?

Look at other dictionaries:

  • Xiongnu — Nomadic confederation 3rd cent. BC–460s AD …   Wikipedia

  • Tilaka — Tilak redirects here. For the Hindu nationalist leader see Bal Gangadhar Tilak. Indian woman with tilaka and bindi In Hinduism, the tilaka or tika or tilak (Sanskrit: तिलक …   Wikipedia

  • Spot blotch (wheat) — Spot blotch is a leaf disease of wheat caused by Cochliobolus sativus .cite book last = Wiese first = M.V. title = Compendium of wheat diseases publisher = American Phytopathological Society date = 1987 pages = 124 pp ] cite book last = Martens… …   Wikipedia

  • Nagendra Kumar Singh — Born October 15, 1958 Mau …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”