KIF3B

KIF3B

Kinesin family member 3B, also known as KIF3B, is a human gene.cite web | title = Entrez Gene: KIF3B kinesin family member 3B| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9371| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene acts as a heterodimer with kinesin family member 3A to aid in chromosome movement during mitosis and meiosis. The encoded protein is a plus end-directed microtubule motor and can interact with the SMC3 subunit of the cohesin complex. In addition, the encoded protein may be involved in the intracellular movement of membranous organelles. This protein and kinesin family member 3A form the kinesin II subfamily of the kinesin superfamily.cite web | title = Entrez Gene: KIF3B kinesin family member 3B| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9371| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Yamazaki H, Nakata T, Okada Y, Hirokawa N |title=KIF3A/B: a heterodimeric kinesin superfamily protein that works as a microtubule plus end-directed motor for membrane organelle transport. |journal=J. Cell Biol. |volume=130 |issue= 6 |pages= 1387–99 |year= 1995 |pmid= 7559760 |doi=
*cite journal | author=Nagase T, Ishikawa K, Nakajima D, "et al." |title=Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. |journal=DNA Res. |volume=4 |issue= 2 |pages= 141–50 |year= 1997 |pmid= 9205841 |doi=
*cite journal | author=Nagata K, Puls A, Futter C, "et al." |title=The MAP kinase kinase kinase MLK2 co-localizes with activated JNK along microtubules and associates with kinesin superfamily motor KIF3. |journal=EMBO J. |volume=17 |issue= 1 |pages= 149–58 |year= 1998 |pmid= 9427749 |doi= 10.1093/emboj/17.1.149
*cite journal | author=Shimizu K, Shirataki H, Honda T, "et al." |title=Complex formation of SMAP/KAP3, a KIF3A/B ATPase motor-associated protein, with a human chromosome-associated polypeptide. |journal=J. Biol. Chem. |volume=273 |issue= 12 |pages= 6591–4 |year= 1998 |pmid= 9506951 |doi=
*cite journal | author=Nonaka S, Tanaka Y, Okada Y, "et al." |title=Randomization of left-right asymmetry due to loss of nodal cilia generating leftward flow of extraembryonic fluid in mice lacking KIF3B motor protein. |journal=Cell |volume=95 |issue= 6 |pages= 829–37 |year= 1999 |pmid= 9865700 |doi=
*cite journal | author=Navarro E, Espinosa L, Adell T, "et al." |title=Expressed sequence tag (EST) phenotyping of HT-29 cells: cloning of ser/thr protein kinase EMK1, kinesin KIF3B, and of transcripts that include Alu repeated elements. |journal=Biochim. Biophys. Acta |volume=1450 |issue= 3 |pages= 254–64 |year= 1999 |pmid= 10395937 |doi=
*cite journal | author=Whitehead JL, Wang SY, Bost-Usinger L, "et al." |title=Photoreceptor localization of the KIF3A and KIF3B subunits of the heterotrimeric microtubule motor kinesin II in vertebrate retina. |journal=Exp. Eye Res. |volume=69 |issue= 5 |pages= 491–503 |year= 1999 |pmid= 10548469 |doi= 10.1006/exer.1999.0724
*cite journal | author=Deloukas P, Matthews LH, Ashurst J, "et al." |title=The DNA sequence and comparative analysis of human chromosome 20. |journal=Nature |volume=414 |issue= 6866 |pages= 865–71 |year= 2002 |pmid= 11780052 |doi= 10.1038/414865a
*cite journal | author=Jimbo T, Kawasaki Y, Koyama R, "et al." |title=Identification of a link between the tumour suppressor APC and the kinesin superfamily. |journal=Nat. Cell Biol. |volume=4 |issue= 4 |pages= 323–7 |year= 2002 |pmid= 11912492 |doi= 10.1038/ncb779
*cite journal | author=Baker SA, Freeman K, Luby-Phelps K, "et al." |title=IFT20 links kinesin II with a mammalian intraflagellar transport complex that is conserved in motile flagella and sensory cilia. |journal=J. Biol. Chem. |volume=278 |issue= 36 |pages= 34211–8 |year= 2003 |pmid= 12821668 |doi= 10.1074/jbc.M300156200
*cite journal | author=Imamura T, Huang J, Usui I, "et al." |title=Insulin-induced GLUT4 translocation involves protein kinase C-lambda-mediated functional coupling between Rab4 and the motor protein kinesin. |journal=Mol. Cell. Biol. |volume=23 |issue= 14 |pages= 4892–900 |year= 2003 |pmid= 12832475 |doi=
*cite journal | author=Colland F, Jacq X, Trouplin V, "et al." |title=Functional proteomics mapping of a human signaling pathway. |journal=Genome Res. |volume=14 |issue= 7 |pages= 1324–32 |year= 2004 |pmid= 15231748 |doi= 10.1101/gr.2334104
*cite journal | author=Zhang Y, Hancock WO |title=The two motor domains of KIF3A/B coordinate for processive motility and move at different speeds. |journal=Biophys. J. |volume=87 |issue= 3 |pages= 1795–804 |year= 2005 |pmid= 15345558 |doi= 10.1529/biophysj.104.039842
*cite journal | author=Haraguchi K, Hayashi T, Jimbo T, "et al." |title=Role of the kinesin-2 family protein, KIF3, during mitosis. |journal=J. Biol. Chem. |volume=281 |issue= 7 |pages= 4094–9 |year= 2006 |pmid= 16298999 |doi= 10.1074/jbc.M507028200
*cite journal | author=Wu Y, Dai XQ, Li Q, "et al." |title=Kinesin-2 mediates physical and functional interactions between polycystin-2 and fibrocystin. |journal=Hum. Mol. Genet. |volume=15 |issue= 22 |pages= 3280–92 |year= 2006 |pmid= 17008358 |doi= 10.1093/hmg/ddl404

PBB_Controls
update_page = yes
require_manual_inspection = no
update_protein_box = yes
update_summary = yes
update_citations = yes


Wikimedia Foundation. 2010.

Игры ⚽ Поможем написать реферат

Look at other dictionaries:

  • Kinesin — Animation of kinesin walking on a microtubule The kinesin dimer attaches to, and mo …   Wikipedia

  • Microtubule — Space filling model of a microtubule segment derived from cryo electron microscopy. The protofilaments are seen running along the axis of the segment. The microtubule (+) end is towards the top of the image.[1] Microtubules are a component of the …   Wikipedia

  • Keratin — Not to be confused with kerogen, carotene, chitin, or creatine. Microscopy of keratin filaments inside cells. Keratin refers to a family of fibrous structural proteins. Keratin is the key structural material making up the outer layer of human… …   Wikipedia

  • Cytoskeleton — The eukaryotic cytoskeleton. Actin filaments are shown in red, microtubules in green, and the nuclei are in blue. The cytoskeleton (also CSK) is a cellular scaffolding or skeleton contained within a cell s cytoplasm and is made out of protein.… …   Wikipedia

  • Microfilament — Actin cytoskeleton of mouse embryo fibroblasts, stained with Fluorescein isothiocyanate phalloidin Microfilaments ( or actin filaments) are the thinnest filaments of the cytoskeleton, a structure found in the cytoplasm of all eukaryotic cells.… …   Wikipedia

  • Actin — G Actin (PDB code: 1j6z). ADP and the divalent cation are highlighted …   Wikipedia

  • Myosin — Part of the myosin II structure. Atoms in the heavy chain are colored red on the left hand side, and atoms in the light chains are colored orange and yellow. Myosins comprise a family of ATP dependent motor proteins and are best known for their… …   Wikipedia

  • Lamin — Nuclear lamins, also known as Class V intermediate filaments, are fibrous proteins providing structural function and transcriptional regulation in the cell nucleus. Nuclear lamins interact with membrane associated proteins to form the nuclear… …   Wikipedia

  • MreB — Procaryotic MreB (PDB code: 1jce) in cartoon representation. The fold of the protein is similar to its eukaryotic counterpart actin. MreB is a protein found in bacteria that has been identified as a homologue of actin, as indicated by… …   Wikipedia

  • Dynein — A dynein complex. Cytoplasmic dynein has two heavy chains with globular head …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”