RALB

V-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein), also known as RALB, is a human gene.cite web | title = Entrez Gene: RALB v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5899| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes a GTP-binding protein that belongs to the small GTPase superfamily and Ras family of proteins. GTP-binding proteins mediate the transmembrane signaling initiated by the occupancy of certain cell surface receptors.cite web | title = Entrez Gene: RALB v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5899| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Hsieh CL, Swaroop A, Francke U |title=Chromosomal localization and cDNA sequence of human ralB, a GTP binding protein. |journal=Somat. Cell Mol. Genet. |volume=16 |issue= 4 |pages= 407–10 |year= 1990 |pmid= 2120779 |doi=
*cite journal | author=Chardin P, Tavitian A |title=Coding sequences of human ralA and ralB cDNAs. |journal=Nucleic Acids Res. |volume=17 |issue= 11 |pages= 4380 |year= 1989 |pmid= 2662142 |doi=
*cite journal | author=Jullien-Flores V, Dorseuil O, Romero F, "et al." |title=Bridging Ral GTPase to Rho pathways. RLIP76, a Ral effector with CDC42/Rac GTPase-activating protein activity. |journal=J. Biol. Chem. |volume=270 |issue= 38 |pages= 22473–7 |year= 1995 |pmid= 7673236 |doi=
*cite journal | author=Jilkina O, Bhullar RP |title=Generation of antibodies specific for the RalA and RalB GTP-binding proteins and determination of their concentration and distribution in human platelets. |journal=Biochim. Biophys. Acta |volume=1314 |issue= 1-2 |pages= 157–66 |year= 1997 |pmid= 8972729 |doi=
*cite journal | author=Ikeda M, Ishida O, Hinoi T, "et al." |title=Identification and characterization of a novel protein interacting with Ral-binding protein 1, a putative effector protein of Ral. |journal=J. Biol. Chem. |volume=273 |issue= 2 |pages= 814–21 |year= 1998 |pmid= 9422736 |doi=
*cite journal | author=Sugihara K, Asano S, Tanaka K, "et al." |title=The exocyst complex binds the small GTPase RalA to mediate filopodia formation. |journal=Nat. Cell Biol. |volume=4 |issue= 1 |pages= 73–8 |year= 2002 |pmid= 11744922 |doi= 10.1038/ncb720
*cite journal | author=Clough RR, Sidhu RS, Bhullar RP |title=Calmodulin binds RalA and RalB and is required for the thrombin-induced activation of Ral in human platelets. |journal=J. Biol. Chem. |volume=277 |issue= 32 |pages= 28972–80 |year= 2002 |pmid= 12034722 |doi= 10.1074/jbc.M201504200
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Chien Y, White MA |title=RAL GTPases are linchpin modulators of human tumour-cell proliferation and survival. |journal=EMBO Rep. |volume=4 |issue= 8 |pages= 800–6 |year= 2004 |pmid= 12856001 |doi= 10.1038/sj.embor.embor899
*cite journal | author=Hernández-Muñoz I, Benet M, Calero M, "et al." |title=rgr oncogene: activation by elimination of translational controls and mislocalization. |journal=Cancer Res. |volume=63 |issue= 14 |pages= 4188–95 |year= 2003 |pmid= 12874025 |doi=
*cite journal | author=Moskalenko S, Tong C, Rosse C, "et al." |title=Ral GTPases regulate exocyst assembly through dual subunit interactions. |journal=J. Biol. Chem. |volume=278 |issue= 51 |pages= 51743–8 |year= 2004 |pmid= 14525976 |doi= 10.1074/jbc.M308702200
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Sidhu RS, Clough RR, Bhullar RP |title=Regulation of phospholipase C-delta1 through direct interactions with the small GTPase Ral and calmodulin. |journal=J. Biol. Chem. |volume=280 |issue= 23 |pages= 21933–41 |year= 2005 |pmid= 15817490 |doi= 10.1074/jbc.M412966200
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Chien Y, Kim S, Bumeister R, "et al." |title=RalB GTPase-mediated activation of the IkappaB family kinase TBK1 couples innate immune signaling to tumor cell survival. |journal=Cell |volume=127 |issue= 1 |pages= 157–70 |year= 2006 |pmid= 17018283 |doi= 10.1016/j.cell.2006.08.034
*cite journal | author=Lim KH, O'Hayer K, Adam SJ, "et al." |title=Divergent roles for RalA and RalB in malignant growth of human pancreatic carcinoma cells. |journal=Curr. Biol. |volume=16 |issue= 24 |pages= 2385–94 |year= 2007 |pmid= 17174914 |doi= 10.1016/j.cub.2006.10.023
*cite journal | author=Smith SC, Oxford G, Baras AS, "et al." |title=Expression of ral GTPases, their effectors, and activators in human bladder cancer. |journal=Clin. Cancer Res. |volume=13 |issue= 13 |pages= 3803–13 |year= 2007 |pmid= 17606711 |doi= 10.1158/1078-0432.CCR-06-2419
*cite journal | author=Yin J, Pollock C, Tracy K, "et al." |title=Activation of the RalGEF/Ral pathway promotes prostate cancer metastasis to bone. |journal=Mol. Cell. Biol. |volume=27 |issue= 21 |pages= 7538–50 |year= 2007 |pmid= 17709381 |doi= 10.1128/MCB.00955-07

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