- ATP6AP1
ATPase, H+ transporting, lysosomal accessory protein 1, also known as ATP6AP1, is a human
gene .cite web | title = Entrez Gene: ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=537| accessdate = ]PBB_Summary
section_title =
summary_text = This gene encodes a component of a multisubunit enzyme (1 mDa MW) that mediates acidification of eukaryotic intracellular organelles. Vacuolar ATPase (V-ATPase) is comprised of a cytosolic V1 (site of the ATP catalytic site) and a transmembrane V0 domain. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. The encoded protein of this gene is approximately 45 kD and may assist in the V-ATPase-mediated acidification of neuroendocrine secretory granules.cite web | title = Entrez Gene: ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=537| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Finbow ME, Harrison MA |title=The vacuolar H+-ATPase: a universal proton pump of eukaryotes. |journal=Biochem. J. |volume=324 ( Pt 3) |issue= |pages= 697–712 |year= 1997 |pmid= 9210392 |doi=
*cite journal | author=Stevens TH, Forgac M |title=Structure, function and regulation of the vacuolar (H+)-ATPase. |journal=Annu. Rev. Cell Dev. Biol. |volume=13 |issue= |pages= 779–808 |year= 1998 |pmid= 9442887 |doi= 10.1146/annurev.cellbio.13.1.779
*cite journal | author=Nelson N, Harvey WR |title=Vacuolar and plasma membrane proton-adenosinetriphosphatases. |journal=Physiol. Rev. |volume=79 |issue= 2 |pages= 361–85 |year= 1999 |pmid= 10221984 |doi=
*cite journal | author=Forgac M |title=Structure and properties of the vacuolar (H+)-ATPases. |journal=J. Biol. Chem. |volume=274 |issue= 19 |pages= 12951–4 |year= 1999 |pmid= 10224039 |doi=
*cite journal | author=Kane PM |title=Introduction: V-ATPases 1992-1998. |journal=J. Bioenerg. Biomembr. |volume=31 |issue= 1 |pages= 3–5 |year= 1999 |pmid= 10340843 |doi=
*cite journal | author=Wieczorek H, Brown D, Grinstein S, "et al." |title=Animal plasma membrane energization by proton-motive V-ATPases. |journal=Bioessays |volume=21 |issue= 8 |pages= 637–48 |year= 1999 |pmid= 10440860 |doi= 10.1002/(SICI)1521-1878(199908)21:8<637::AID-BIES3>3.0.CO;2-W |doilabel=10.1002/(SICI)1521-1878(199908)21:8637::AID-BIES33.0.CO;2-W
*cite journal | author=Yokoi H, Hadano S, Kogi M, "et al." |title=Isolation of expressed sequences encoded by the human Xq terminal portion using microclone probes generated by laser microdissection. |journal=Genomics |volume=20 |issue= 3 |pages= 404–11 |year= 1994 |pmid= 8034313 |doi= 10.1006/geno.1994.1194
*cite journal | author=Sedlacek Z, Korn B, Konecki DS, "et al." |title=Construction of a transcription map of a 300 kb region around the human G6PD locus by direct cDNA selection. |journal=Hum. Mol. Genet. |volume=2 |issue= 11 |pages= 1865–9 |year= 1994 |pmid= 8281148 |doi=
*cite journal | author=Chen EY, Zollo M, Mazzarella R, "et al." |title=Long-range sequence analysis in Xq28: thirteen known and six candidate genes in 219.4 kb of high GC DNA between the RCP/GCP and G6PD loci. |journal=Hum. Mol. Genet. |volume=5 |issue= 5 |pages= 659–68 |year= 1997 |pmid= 8733135 |doi=
*cite journal | author=Holthuis JC, Jansen EJ, Schoonderwoert VT, "et al." |title=Biosynthesis of the vacuolar H+-ATPase accessory subunit Ac45 in Xenopus pituitary. |journal=Eur. J. Biochem. |volume=262 |issue= 2 |pages= 484–91 |year= 1999 |pmid= 10336633 |doi=
*cite journal | author=Hartley JL, Temple GF, Brasch MA |title=DNA cloning using in vitro site-specific recombination. |journal=Genome Res. |volume=10 |issue= 11 |pages= 1788–95 |year= 2001 |pmid= 11076863 |doi=
*cite journal | author=Bagai S, Rubio E, Cheng JF, "et al." |title=Fibroblast growth factor-10 is a mitogen for urothelial cells. |journal=J. Biol. Chem. |volume=277 |issue= 26 |pages= 23828–37 |year= 2002 |pmid= 11923311 |doi= 10.1074/jbc.M201658200
*cite journal | author=Hodi FS, Schmollinger JC, Soiffer RJ, "et al." |title=ATP6S1 elicits potent humoral responses associated with immune-mediated tumor destruction. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 10 |pages= 6919–24 |year= 2002 |pmid= 11983866 |doi= 10.1073/pnas.102025999
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899PBB_Controls
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