Feline sarcoma oncogene

Feline sarcoma oncogene, also known as FES, is a human gene.cite web | title = Entrez Gene: FES feline sarcoma oncogene| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2242| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. The gene product has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis. A truncated transcript has been identified that is generated utilizing a start site in one of the far downstream exons but a protein product associated with this transcript has not been identified.cite web | title = Entrez Gene: FES feline sarcoma oncogene| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2242| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Smithgall TE, Rogers JA, Peters KL, "et al." |title=The c-Fes family of protein-tyrosine kinases. |journal=Critical reviews in oncogenesis |volume=9 |issue= 1 |pages= 43–62 |year= 1998 |pmid= 9754447 |doi=
*cite journal | author=Jiang H, Harris MB, Rothman P |title=IL-4/IL-13 signaling beyond JAK/STAT. |journal=J. Allergy Clin. Immunol. |volume=105 |issue= 6 Pt 1 |pages= 1063–70 |year= 2000 |pmid= 10856136 |doi=
*cite journal | author=Greer P |title=Closing in on the biological functions of Fps/Fes and Fer. |journal=Nat. Rev. Mol. Cell Biol. |volume=3 |issue= 4 |pages= 278–89 |year= 2002 |pmid= 11994747 |doi= 10.1038/nrm783

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