- Urea transporter
An urea transporter is a
membrane transport protein , transportingurea .Urea Transporter A1
Urea transporter 1 transports urea across the
apical membrane into the intracellular space of luminal cells in theinner medullary collecting duct of thekidneys . UT-1 is activated by ADH, but is a passive transporter. It reabsorbs up to 40% of the original filtered load of urea. cite journal| title = Urea and Renal Function in the 21st Century: Insights from Knockout Mice
author = Robert A. Fenton and Mark A. Knepper| journal = J Am Soc Nephrol | year = 2007| issue = 18| pages = 679–688, 2007
doi = 10.1681/ASN.2006101108| volume = 18 ]Urea Transporter A2
Urea Transporter 2 transports urea across the
apical membrane into the luminal space of cells in thethin descending loop of Henle of thekidneys .cite journal| title = Urea and Renal Function in the 21st Century: Insights from Knockout Mice
author = Robert A. Fenton and Mark A. Knepper| journal = J Am Soc Nephrol | year = 2007| issue = 18| pages = 679–688, 2007
doi = 10.1681/ASN.2006101108| volume = 18 ]Urea Transporter A3
Urea transporter 3 transports urea into the interstitium of the Inner Medullary Collecting Duct.cite journal| title = Urea transporter UT-A | journal = Nature molecule page | year = 2005
doi = 10.1038/mp.a002589.01| author = Fenton, R. A.| volume = 18| pages = 679 ]Urea Transporter A4
Urea transporter 4 has been detected in rat but not mouse kidney medulla.cite journal| title = Urea transporter UT-A | journal = Nature molecule page | year = 2005
doi = 10.1038/mp.a002589.01| author = Fenton, R. A.| volume = 18| pages = 679 ]Urea Transporter A5
Urea transporter 5 is not expressed in the kidney but in the testis.cite journal| title = Urea transporter UT-A | journal = Nature molecule page | year = 2005
doi = 10.1038/mp.a002589.01| author = Fenton, R. A.| volume = 18| pages = 679 ]Urea Transporter B
UT-B is expressed in the basolateral and apical regions of the descending
Vasa recta .cite journal| title = Urea and Renal Function in the 21st Century: Insights from Knockout Mice
author = Robert A. Fenton and Mark A. Knepper| journal = J Am Soc Nephrol | year = 2007| issue = 18| pages = 679–688, 2007
doi = 10.1681/ASN.2006101108| volume = 18 ]References
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