Ethionine

Ethionine

Chembox new
ImageFile = ethionine.png ImageSize =
IUPACName = 2-Amino-4-ethylsulfanylbutyric acid
OtherNames = S-Ethyl-L-homocysteine
Section1 = Chembox Identifiers
CASNo = 13073-35-3
PubChem = 25674
SMILES = CCSCC [C@@H] (C(=O)O)N
Section2 = Chembox Properties
Formula = C6H13NO2S
MolarMass = 163.239 g/mol
Appearance =
Density =
MeltingPt =
BoilingPt =
Solubility =
Section3 = Chembox Hazards
MainHazards =
FlashPt =
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Ethionine is a non-proteinogenic amino acid structurally related to methionine, with an ethyl group in place of the methyl group.

Ethionine is an antimetabolite and methionine antagonist. It prevents amino acid incorporation into proteins and interferes with cellular use of adenosine triphosphate (ATP). Because of these pharmacological effects, ethionine is highly toxic and is a potent carcinogen. [cite journal|title=Hypomethylation of DNA in ethionine-fed rats|author=Narayan Shivapurkar, Mary J. Wilson and Lionel A. Poirier |journal=Carcinogensis|volume =5|issue=8|pages=989–992|year=1984|doi=10.1093/carcin/5.8.989|pmid=6744518]

References

External links


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Look at other dictionaries:

  • ethionine — etioninas statusas T sritis chemija formulė C₂H₅SCH₂CH₂CH(NH₂)COOH atitikmenys: angl. ethionine rus. этионин ryšiai: sinonimas – 2 amino 4 etiltiobutano rūgštis …   Chemijos terminų aiškinamasis žodynas

  • ethionine — noun Date: 1938 an amino acid C6H13NO2S that is the ethyl homologue of methionine and is biologically antagonistic to methionine …   New Collegiate Dictionary

  • ethionine — noun A toxic and carcinogenic non proteinogenic amino acid structurally related to methionine, with an ethyl group in place of the methyl group …   Wiktionary

  • ethionine — A methionine analog and antagonist, differing in the presence of an S ethyl group in place of the S methyl group. * * * ethi·o·nine e thī ə .nēn n an amino acid C6H13NO2S that is the ethyl homologue of methionine and is biologically antagonistic… …   Medical dictionary

  • ethionine — ethi·o·nine …   English syllables

  • ethionine — eˈthīəˌnēn, nə̇n noun ( s) Etymology: eth + ionine (as in methionine) : a crystalline amino acid C2H5SCH2CH2CH(NH2)COOH that is the ethyl homologue of methionine and is biologically antagonistic to methionine …   Useful english dictionary

  • antimetabolite — A substance that competes with, replaces, or antagonizes a particular metabolite; e.g., ethionine is an a. of methionine. * * * an·ti·me·tab·o·lite .ant i mə tab ə .līt, .an .tī n a substance (as a sulfa drug) that replaces or inhibits the… …   Medical dictionary

  • AUXINES — Les auxines sont des régulateurs de croissance qui, chez les plantes supérieures, sont synthétisés principalement dans les bourgeons. Elles contrôlent la croissance des cellules dérivées des méristèmes primaires et la multiplication des cellules… …   Encyclopédie Universelle

  • FOIE — L’importance biologique du foie humain est attestée par son volume et par sa densité cellulaire; il pèse environ 1,5 kg chez l’adulte et représente le 1/50 du poids du corps, formant ainsi la masse viscérale la plus volumineuse de l’organisme,… …   Encyclopédie Universelle

  • etioninas — statusas T sritis chemija formulė C₂H₅SCH₂CH₂CH(NH₂)COOH atitikmenys: angl. ethionine rus. этионин ryšiai: sinonimas – 2 amino 4 etiltiobutano rūgštis …   Chemijos terminų aiškinamasis žodynas

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