Chlorophyll synthase

Chlorophyll synthase
chlorophyll synthase
Identifiers
EC number 2.5.1.62
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a chlorophyll synthase (EC 2.5.1.62) is an enzyme that catalyzes the chemical reaction

chlorophyllide a + phytyl diphosphate \rightleftharpoons chlorophyll a + diphosphate

Thus, the two substrates of this enzyme are chlorophyllide a and phytyl diphosphate, whereas its two products are chlorophyll a and diphosphate.

This enzyme belongs to the family of transferases, specifically those transferring aryl or alkyl groups other than methyl groups. The systematic name of this enzyme class is chlorophyllide-a:phytyl-diphosphate phytyltransferase. This enzyme participates in porphyrin and chlorophyll metabolism.

References

  • Schmid HC, Rassadina V, Oster U, Schoch S, Rudiger W (2002). "Pre-loading of chlorophyll synthase with tetraprenyl diphosphate is an obligatory step in chlorophyll biosynthesis". Biol. Chem. 383 (11): 1769–78. doi:10.1515/BC.2002.198. PMID 12530542. 
  • Oster U, Bauer CE, Rudiger W (1997). "Characterization of chlorophyll a and bacteriochlorophyll a synthases by heterologous expression in Escherichia coli". J. Biol. Chem. 272 (15): 9671–6. doi:10.1074/jbc.272.15.9671. PMID 9092496. 
  • Rudiger W, Benz J, Guthoff C (1980). "Detection and partial characterization of activity of chlorophyll synthetase in etioplast membranes". Eur. J. Biochem. 109 (1): 193–200. doi:10.1111/j.1432-1033.1980.tb04784.x. PMID 7408876.