P2RY4

P2RY4
Pyrimidinergic receptor P2Y, G-protein coupled, 4
Identifiers
Symbols P2RY4; NRU; P2P; P2Y4; UNR
External IDs OMIM300038 MGI1926594 HomoloGene20568 IUPHAR: P2Y4 GeneCards: P2RY4 Gene
RNA expression pattern
PBB GE P2RY4 221466 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 5030 57385
Ensembl ENSG00000186912 ENSMUSG00000044359
UniProt P51582 Q0VBT7
RefSeq (mRNA) NM_002565 NM_020621.4
RefSeq (protein) NP_002556 NP_065646.1
Location (UCSC) Chr X:
69.48 – 69.48 Mb
Chr X:
97.79 – 97.79 Mb
PubMed search [1] [2]

P2Y purinoceptor 4 is a protein that in humans is encoded by the P2RY4 gene.[1][2]

The product of this gene, P2Y4, belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is responsive to uridine nucleotides, partially responsive to ATP, and not responsive to ADP.[2]

Contents

See also

References

  1. ^ Communi D, Pirotton S, Parmentier M, Boeynaems JM (Feb 1996). "Cloning and functional expression of a human uridine nucleotide receptor". J Biol Chem 270 (52): 30849–52. doi:10.1074/jbc.270.52.30849. PMID 8537336. 
  2. ^ a b "Entrez Gene: P2RY4 pyrimidinergic receptor P2Y, G-protein coupled, 4". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5030. 

External links

Further reading

Metabolites and
signaling molecules
Peptide
Miscellaneous
Class B: Secretin like Class C: Metabotropic
glutamate / pheromone Class F:
Frizzled / Smoothened B trdu: iter (nrpl/grfl/cytl/horl), csrc (lgic, enzr, gprc, igsr, intg, nrpr/grfr/cytr), itra (adap, gbpr, mapk), calc, lipd; path (hedp, wntp, tgfp+mapp, notp, jakp, fsap, hipp, tlrp)

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Look at other dictionaries:

  • P2Y receptor — P2Y receptors are a family of purinergic receptors, G protein coupled receptors stimulated by nucleotides such as ATP, ADP, UTP, UDP and UDP glucose. To date, 12 P2Y receptors have been cloned in humans: P2Y1, P2Y2, P2Y4, P2Y5, P2Y6, P2Y8, P2Y9… …   Wikipedia

  • Rhodopsin-like receptors — Pfam box Symbol = 7tm 1 Name = Rhodopsin like receptors width = caption = Pfam= PF00001 InterPro= IPR000276 SMART= PROSITE = PDOC00211 SCOP = 1f88 TCDB = OPM family= 6 OPM protein= 1gzm PDB=Rhodopsin like receptors are the largest group of G… …   Wikipedia

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