2,4-diaminopentanoate dehydrogenase

In enzymology, a 2,4-diaminopentanoate dehydrogenase (EC number|1.4.1.12) is an enzyme that catalyzes the chemical reaction

:2,4-diaminopentanoate + H₂O + NAD(P)+ $ightleftharpoons$ 2-amino-4-oxopentanoate + NH₃ + NAD(P)H + H⁺

The 4 substrates of this enzyme are 2,4-diaminopentanoate, H₂O, NAD⁺, and NADP⁺, whereas its 5 products are 2-amino-4-oxopentanoate, NH₃, NADH, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH2 group of donors with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 2,4-diaminopentanoate:NAD(P)+ oxidoreductase (deaminating). This enzyme is also called 2,4-diaminopentanoic acid C4 dehydrogenase. This enzyme participates in 3 metabolic pathways: lysine degradation, arginine and proline metabolism, and d-arginine and d-ornithine metabolism.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|39346-26-4."

Gene Ontology (GO) codes