(ribulose-bisphosphate carboxylase)-lysine N-methyltransferase

(ribulose-bisphosphate carboxylase)-lysine N-methyltransferase

In enzymology, a [ribulose-bisphosphate carboxylase] -lysine N-methyltransferase (EC number|2.1.1.127) is an enzyme that catalyzes the chemical reaction

:S-adenosyl-L-methionine + [ribulose-1,5-bisphosphate carboxylase] -lysine ightleftharpoons S-adenosyl-L-homocysteine + [ribulose-1,5-bisphosphate carboxylase] -N6-methyl-L-lysine

Thus, the two substrates of this enzyme are S-adenosyl methionine and [ribulose-1,5-bisphosphate carboxylase-lysine] , whereas its two products are S-adenosylhomocysteine and [ribulose-1,5-bisphosphate carboxylase-N6-methyl-L-lysine] .

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine: [3-phospho-D-glycerate-carboxy-lyase (dimerizing)] -lysine N6-methyltransferase. Other names in common use include rubisco methyltransferase, ribulose-bisphosphate-carboxylase/oxygenase N-methyltransferase, ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit, epsilonN-methyltransferase, S-adenosyl-L-methionine: [3-phospho-D-glycerate-carboxy-lyase, and (dimerizing)] -lysine 6-N-methyltransferase.

tructural studies

As of late 2007, 7 structures have been solved for this class of enzymes, with PDB accession codes PDB link|1MLV, PDB link|1OZV, PDB link|1P0Y, PDB link|2H21, PDB link|2H23, PDB link|2H2E, and PDB link|2H2J.

References

*
*

External links

::"The CAS registry number for this enzyme class is CAS registry|139171-98-5."

Gene Ontology (GO) codes


Wikimedia Foundation. 2010.

Игры ⚽ Нужно сделать НИР?

Look at other dictionaries:

  • N-methyltransferase — may refer to (RS) 1 benzyl 1,2,3,4 tetrahydroisoquinoline N methyltransferase 3 hydroxy 16 methoxy 2,3 dihydrotabersonine N methyltransferase Amine N methyltransferase Anthranilate N methyltransferase (cytochrome c) arginine N methyltransferase… …   Wikipedia

  • List of EC numbers (EC 2) — This list contains a list of EC numbers for the second group, EC 2, transferases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 2.1: Transferring One… …   Wikipedia

  • Metabolism — Cell metabolism redirects here. For the journal, see Cell Metabolism. Structure of adenosine triphosphate, a central intermediate in energy metabolism Metabolism (from Greek: μεταβολή metabolē , change or Greek: μεταβολισμός metabolismos,… …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”