Ceftizoxime

Ceftizoxime
Ceftizoxime
Systematic (IUPAC) name
(6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Clinical data
Trade names Cefizox
AHFS/Drugs.com Consumer Drug Information
MedlinePlus a684043
Pregnancy cat.  ?
Legal status  ?
Identifiers
CAS number 68401-81-0 68401-82-1
ATC code J01DD07
PubChem CID 6533629
ChemSpider 5018818
UNII C43C467DPE YesY
KEGG D07658
ChEMBL CHEMBL528
Chemical data
Formula C13H13N5O5S2 
Mol. mass 383.405 g/mol

Ceftizoxime is a parenteral third-generation cephalosporin. Unlike other 3rd generation cephalosporins , in ceftizoxime the whole C-3 side chain has been removed to prevent deactivation by hydrolytic enzymes . It rather resembles Cefotaxime in its properties , however not being subjected to metabolism .

Penems
Biapenem • Ertapenem • antipseudomonal (Doripenem • Imipenem • Meropenem) • Panipenem
Cefixime# • Ceftriaxone# • antipseudomonal (Ceftazidime# • Cefoperazone) • Cefcapene • Cefdaloxime • Cefdinir • Cefditoren • Cefetamet • Cefmenoxime • Cefodizime • Cefotaxime • Cefpimizole • Cefpiramide • Cefpodoxime • Cefsulodin • Cefteram • Ceftibuten • Ceftiolene • Ceftizoxime • oxacephem (Flomoxef, Latamoxef ‡)
4th (antips-)
Ceftobiprole • Ceftaroline fosamil
Aztreonam • Tigemonam • Carumonam • Tabtoxin
Combinations
Other
polymyxins/detergent (Colistin, Polymyxin B) • depolarizing (Daptomycin) • hydrolyze NAM-NAG (Lysozyme) • Gramicidin

M: BAC

bact (clas)

gr+f/gr+a(t)/gr-p(c)/gr-o

drug(J1p, w, n, m, vacc)

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