Protein-bound paclitaxel

Protein-bound paclitaxel

Protein-bound paclitaxel is an injectable formulation of paclitaxel, a mitotic inhibitor drug used in the treatment of breast cancer. [cite web |url= http://www.cancer.gov/Templates/db_alpha.aspx?CdrID=507751 |title= Definition of "protein-bound paclitaxel" |publisher= National Cancer Institute Dictionary of Cancer Terms ] In this formulation, paclitaxel is bonded to albumin as a delivery vehicle. It is sold in the United States under the trade name [http://www.abraxane.com Abraxane] by [http://www.abraxisbio.com Abraxis Bioscience] . [cite web |url= http://www.cancer.gov/cancertopics/druginfo/nanoparticlepaclitaxel |title= Paclitaxel Albumin-stabilized Nanoparticle Formulation |publisher= National Cancer Institute Drug Information ]

This treatment was approved by the Food and Drug Administration in January 2005 for cases where cancer did not respond to other chemotherapy or has relapsed. [cite web |url= http://www.cancer.gov/cancertopics/druginfo/fda-nanoparticle-paclitaxel |title= FDA Approval for Nanoparticle Paclitaxel |publisher= National Cancer Institute Drug Information ]

Abraxane is a firstFact|date=February 2008 in its class of drugs using nanoparticle albumin bound (nab) technology platform. [http://www.abraxisbio.com/rnd_platform_nab.htm nab Technology]

References


Wikimedia Foundation. 2010.

Игры ⚽ Нужно решить контрольную?

Look at other dictionaries:

  • protein-bound paclitaxel — A drug used to treat breast cancer that has spread or that has come back within 6 months after chemotherapy. It is also being studied in the treatment of newly diagnosed breast cancer and other types of cancer. Protein bound paclitaxel belongs to …   English dictionary of cancer terms

  • Paclitaxel (Albumin-Stabilized Nanoparticle Formulation) — A drug used to treat breast cancer that has spread or that has come back within 6 months after chemotherapy. It is also being studied in the treatment of newly diagnosed breast cancer and other types of cancer. Paclitaxel (Albumin Stabilized… …   English dictionary of cancer terms

  • Paclitaxel — Systematic (IUPAC) name (2α,4α,5β,7β,10β,13α) 4,10 bis(acetyloxy) …   Wikipedia

  • nanoparticle paclitaxel — A drug used to treat breast cancer that has spread or that has come back within 6 months after chemotherapy. It is also being studied in the treatment of newly diagnosed breast cancer and other types of cancer. Nanoparticle paclitaxel belongs to… …   English dictionary of cancer terms

  • Chemotherapy — A woman being treated with docetaxel chemotherapy for breast cancer. Cold mittens and wine coolers are placed on her hands and feet to reduce harm to her nails. Chemotherapy (sometimes cancer chemotherapy) is the treatment of cancer with an… …   Wikipedia

  • ABI-007 — A drug used to treat breast cancer that has spread or that has come back within 6 months after chemotherapy. It is also being studied in the treatment of newly diagnosed breast cancer and other types of cancer. ABI 007 is a type of mitotic… …   English dictionary of cancer terms

  • Abraxane — A drug used to treat breast cancer that has spread or that has come back within 6 months after chemotherapy. It is also being studied in the treatment of newly diagnosed breast cancer and other types of cancer. Abraxane belongs to the family of… …   English dictionary of cancer terms

  • Docetaxel — [1] Docetaxel Systematic (IUPAC) name 1,7β,10β trihydroxy 9 oxo 5β,20 epoxytax 11 ene 2α,4,13α triyl 4 acetate 2 benzoate 13 {(2R,3S) 3 [(tert butoxycarbonyl)amino] 2 hydroxy …   Wikipedia

  • Medicinal mushrooms — Lepista nuda Medicinal mushrooms are mushrooms, or mushroom extracts, that are used or studied as possible treatments for diseases. Lentinula edodes (shiitake), Grifola frondosa (maitake), Ganoderma lucidum (mannentake), and Cordyceps, have a… …   Wikipedia

  • Discovery and development of tubulin inhibitors — Tubulin inhibitors interfere directly with the tubulin system which is in contrast to those drugs acting on DNA for cancer chemotherapy. Microtubules play an important role in eukaryotic cells. Alpha and beta tubulin, the main components of… …   Wikipedia

Share the article and excerpts

Direct link
… Do a right-click on the link above
and select “Copy Link”