Tombus virus defective interfering (DI) RNA region 3

Tombus virus defective interfering (DI) RNA region 3

Tombus virus defective interfering (DI) RNA region 3 is an important cis-regulatory region identified in the 3'UTR of Tombus virus defective interfering (DI) particles (DI)cite journal | author = Ray D, White KA | title = An internally located RNA hairpin enhances replication of Tomato bushy stunt virus RNAs | journal = J. Virol. | volume = 77 | issue = 1 | pages = 245–57 | year = 2003 | pmid = 12477830 | doi = ] .

Defective interfering RNAs are small sub-viral replicons which are non-coding deletion mutants of the virus that maintain cis-acting RNA elements necessary for replication of the host virus . This conserved region of the 3'UTR has been found to enhance DI RNA accumulation by approximately 10-fold as well as mediating viral replication.

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  • Tombusvirus 5' UTR — is an important cis regulatory region of the Tombus virus genome. Tomato bushy stunt virus is the prototype member of the Tombusviridae family. The genome of this virus is positive sense single stranded RNA. Replication occurs via a negative… …   Wikipedia

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