Connexin-43 internal ribosome entry site (IRES)

Connexin-43 internal ribosome entry site (IRES)
Predicted secondary structure and sequence conservation of IRES_Cx43
Identifiers
Symbol	IRES_Cx43
Rfam	RF00487
Other data
RNA type	Cis-reg; IRES
Domain(s)	Eukaryota
GO	0043022
SO	0000243

The connexin-43 internal ribosome entry site (IRES) is an RNA element present in the 5' UTR of the mRNA of connexin-43 and allows cap-independent translation. The connexin-43 internal ribosome entry site (IRES) allows cap independent translation during conditions such as heat shock and stress.^[1]

References

1. ^ Schiavi, A; Hudder A, Werner R (1999). "Connexin43 mRNA contains a functional internal ribosome entry site". FEBS Lett 464 (3): 118–122. doi:10.1016/S0014-5793(99)01699-3. PMID 10618489. 

External links

• Rfam page for Connexin-43 internal ribosome entry site (IRES)