Deiodinase


Deiodinase

Deiodinase (or iodide peroxidase or "Monodeiodinase") is a peroxidase enzyme that is involved in the activation or deactivation of thyroid hormones. In general, T4 (thyroxine) is converted into T3 (triiodothyronine) by the deiodinase enzyme in target cells.

Types of deiodinases include:

family prosthetic group genes
Iodothyronine deiodinase selenium DIO1, DIO2, DIO3
Iodotyrosine deiodinase flavin IYD

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