Azaserine

Azaserine

drugbox
IUPAC_name = "O"-(2-Diazoacetyl)-L-serine


CAS_number = 115-02-6
ATC_prefix =
ATC_suffix =
PubChem = 5284344
DrugBank =
C=5 | H= 7 | N=3 | O=4
molecular_weight = 173.127 g/mol
bioavailability =
protein_bound =
metabolism =
elimination_half-life =
excretion =
pregnancy_AU =
pregnancy_US =
pregnancy_category=
legal_AU =
legal_CA =
legal_UK =
legal_US =
legal_status =
routes_of_administration =

Azaserine is a carcinogen primarily used for researching pancreatic cancer in animal models. It is a glutamine analogue that irreversibly inhibits , which is involved in the biosynthesis of Inosine monophosphate (IMP). IMP is an important precursor to the purine nucleotides which include Adenosine monophosphate (AMP) and Guanosine monophosphate (GMP).


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