Dystrophic calcification


Dystrophic calcification

Dystrophic Calcification (D.C.) is the mineralization of soft tissue without a systemic mineral imbalance. (A systemic imbalance would elevate calcium levels in the blood and all tissues: metastatic calcification.) This occurs as a reaction to tissue damage,cite web |url=http://library.med.utah.edu/WebPath/CINJHTML/CINJ047.html |title=Cell Injury |format= |work= |accessdate=] including as a consequence of medical device implantation.

Dystrophic calcification can occur in a eucalcemic state. Basophilic calcium salt deposits aggregate, first in the mitochondria, and progressively throughout the cell. These calcifications are an indication of previous cell injury on the microscopic level.

Calcification can occur in dead or degenerated tissue

Calcification in dead tissue

#Caseous necrosis in T.B. is most common site of dystrophic calcification.
#Liquefactive necrosis in chronic abscesses may get calcified.
#Fat necrosis following acute pancreatitis or traumatic fat necrosis in breasts results in deposition of calcium soaps.
#Infarcts may undergo D.C.
#Thrombi, esp. in veins, may produce phleoboliths.
#Haematomas in the vicinity of bones may undergo D.C.
#Dead parasites like schistostoma eggs show D.C.
#Congenital toxoplasmosis involving CNS visualised by calcification in infaract brain.

Calcification in degenerated tissue

#Dense scars may undergo hyaline degeneration and calcification.
#Atheroma in aorta and coronaries frequently undergo calcification.
#Cysts can show calcifcation.
#Calcinosis cutis is condition in which there are irregular nodular deposits of calcium salts in skin and subcutaneous tissue.
#Senile degenerative changes may be accompanied by calcification.

ee also

*Calcinosis
*Monckeberg's arteriosclerosis

References


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Look at other dictionaries:

  • dystrophic calcification — the calcification of injured or necrotic tissue in the absence of systemic hypercalcaemia. Dystrophic calcification is a characteristic feature in some cancers of the breast, ovary, and thyroid gland. Compare: metastatic calcification …   The new mediacal dictionary

  • dystrophic calcification — noun mineralization of soft tissues occurring without a systemic mineral imbalance …   Wiktionary

  • dystrophic calcification — the deposition of calcium in abnormal locations, such as scar tissue or atherosclerotic plaques, but without abnormalities of blood calcium. See also calcinosis …   Medical dictionary

  • Calcification — This article is about calcification of body tissue. For calcification of water pipes, see Hard water Calcification is the process in which calcium salts build up in soft tissue, causing it to harden. Calcifications may be classified on whether… …   Wikipedia

  • dystrophic — Relating to dystrophy. * * * dys·tro·phic dis trō fik adj 1) relating to or caused by faulty nutrition 2) relating to or affected with a dystrophy <dystrophic muscles> 3 a) occurring at sites of damaged or necrotic tissue <dystrophic… …   Medical dictionary

  • calcification — n. the deposition of calcium salts in tissue. This occurs as part of the normal process of bone formation (see ossification). Compare: dystrophic calcification, metastatic calcification …   The new mediacal dictionary

  • Calcification — The process of building bone by suffusing tissues with calcium salts. Also called ossification. * * * 1. Deposition of lime or other insoluble calcium salts. 2. A process in which tissue or noncellular material in the body becomes hardened as the …   Medical dictionary

  • Metastatic calcification — is deposition of calcium salts in otherwise normal tissue, because of elevated serum levels of calcium in blood,[1] which can occur because of deranged metabolism as well as increased absorption or decreased excretion of calcium and related… …   Wikipedia

  • metastatic calcification — the calcification of otherwise normal tissues in patients with hypercalcaemia. Compare: dystrophic calcification …   The new mediacal dictionary

  • Calcinosis cutis — Classification and external resources ICD 10 L94.2 ICD 9 709.3 …   Wikipedia


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