Cyclazocine

Cyclazocine
Cyclazocine
Systematic (IUPAC) name
3-(cyclopropylmethyl)- 6,11-dimethyl- 1,2,3,4,5,6-hexahydro- 2,6-methano- 3-benzazocin- 8-ol
or
2-cyclopr​opylmethy​l- 2'-hydr​oxy- 5,9-d​imethyl- 6​,7-benzom​orphan
Clinical data
Pregnancy cat.  ?
Legal status  ?
Routes Oral
Identifiers
CAS number 7346-09-0 N
ATC code None
PubChem CID 19143
IUPHAR ligand 1604
ChemSpider 18063 YesY
UNII J5W1B1159C YesY
KEGG D03618 YesY
ChEMBL CHEMBL279449 N
Chemical data
Formula C18H25NO 
Mol. mass 271.40 g/mol
SMILES eMolecules & PubChem
 N(what is this?)  (verify)

Cyclazocine is a mixed opioid agonist/antagonist related to dezocine, pentazocine and phenazocine. This family of opioid drugs is called the benzomorphans or benzazocines.[1]

Contents

Use

Research into the use of cyclazocine for the treatment of bipolar patients with depression was undertaken by Fink and colleagues (1970). It showed that 8 out of 10 patients experienced moderate improvement.

Research during the 1960s and 1970s into the possible use of cyclazocine for management of pain, and later for assisting treatment of narcotic addiction was severely hampered by the drug's psychotomimetic, dysphoric, and hallucinatory effects.[2]

Dosage

Dosages of 1–3 mg were administered in the tests.

See also

  • Benzomorphan

References


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Look at other dictionaries:

  • cyclazocine — [sī΄klə zō′sēn΄, sī΄klə zō′sin] n. [ CYCL(O) + (PENTA)ZOCINE] a painkilling, nonaddictive, synthetic drug, C18H25NO, that blocks the effects of heroin or morphine …   English World dictionary

  • cyclazocine — noun Etymology: cycl + azocine (C7H7N), probably from az + octa + 2 ine Date: 1966 an analgesic drug C18H25NO that inhibits the effect of morphine and related addictive drugs and is used in the treatment of drug addictio …   New Collegiate Dictionary

  • cyclazocine — /suy klaz euh seen , sin, suy kleuh zoh seen, sin/, n. Pharm. a synthetic nonnarcotic and nonaddictive analgesic, C18H25NO, that blocks the effects of morphine or morphinelike drugs: used to treat heroin or morphine addiction. [contr. and alter.… …   Universalium

  • cyclazocine — noun A particular narcotic …   Wiktionary

  • cyclazocine — cy·claz·o·cine sī klaz ə .sēn, sən n an analgesic drug C18H25NO that inhibits the effect of morphine and related addictive drugs and is used in the treatment of drug addiction * * * cy·cla·zo·cine (si″klə zoґsēn) a narcotic… …   Medical dictionary

  • cyclazocine — cy·claz·o·cine …   English syllables

  • cyclazocine —   n. synthetic drug protecting against the addictive effects of the morphine group …   Dictionary of difficult words

  • cyclazocine — sīˈklazəˌsēn, sə̇n noun ( s) Etymology: cycl + azocine (as in phenazocine herein) : an analgesic drug C18H25NO that inhibits the effect of morphine and related addictive drugs and is used in the treatment of drug addiction * * * /suy klaz euh… …   Useful english dictionary

  • cyc — cyclazocine; cycle; cyclotron * * * cyclophosphamide …   Medical dictionary

  • cyc — • cyclazocine; • cycle; • cyclotron …   Dictionary of medical acronyms & abbreviations

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